Results 81 to 90 of about 79,372 (334)
Aggregate, EarlyView.Herein, we report a quinolinium‐based fluorescent probe, PA‐2, for near‐infrared super‐resolution imaging of lysosomal dynamics. Building on this, we next introduce a novel approach leveraging a large multimodal model (LMM), an advanced artificial intelligence tool, for automated image interpretation.
Rui Chen +7 more
wiley +1 more source
Nature Communications, 2021 The large and small subunits of the ribosome are synthesized independently within the nucleolus — a membrane-less compartment within the nucleus — before being exported into the cytoplasm.
Philipp S. Erdmann +7 more
doaj +1 more source
Hand it to the nucleolus [PDF]
The Journal of Cell Biology, 2007 Long viewed as merely a biofactory for ribosomes, the nucleolus has recently come to be seen as a multifunctional and dynamic subnuclear organelle. New support for this view comes from a study by David Martindill, Paul Riley (UCL Institute of Child Health, London, UK), and colleagues, who show that a cell fate regulator is held inactive in the ...
openaire +2 more sources
Advanced Intelligent Systems, EarlyView.Autofluorescence imaging with virtual histological staining streamlines postoperative histopathology. Using a deep ultraviolet light‐emitting diode (LED)‐based imaging system and a weakly supervised deep learning model, virtual hematoxylin and eosin (H&E)‐stained images are generated from the autofluorescence of prostate tissue. Pathologist evaluations
Mingxuan Si +9 more
wiley +1 more source
The Multiple Functions of the Nucleolus in Plant Development, Disease and Stress Responses
Frontiers in Plant Science, 2018 The nucleolus is the most conspicuous domain in the eukaryotic cell nucleus, whose main function is ribosomal RNA (rRNA) synthesis and ribosome biogenesis.
Natalia O. Kalinina +5 more
doaj +1 more source
Matching games: the least core and the nucleolus [PDF]
, 2000 A matching game is a cooperative game defined by a graph $G=(V,E)$. The player set is $V$ and the value of a coalition $S \subseteq V$ is defined as the size of a maximum matching in the subgraph induced by $S$.
Kern, W., Paulusma, D.
core +1 more source
Effect of Urtica dioica L extract on quantitative morphometric alterations of liver parenchymal cells in STZ diabetic rats [PDF]
, 2009 Diabetes is associated with several structural and functional liver abnormalities that affect glycogen and lipid metabolism. In this study, an attempt was made to evaluate the effects of hydroalcoholic extract of Urtica dioica leaves on Quantitative ...
Farsi, M.M. +2 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.At steady state, DRG ensures low‐level expression of TH+ neurons under the protection of AKT. However, the DRG level of PD mouse model under MPTP toxicity increased significantly, and the expression of IL‐6 and CASP3 increased. This process was accompanied by the occurrence of m6A demethylation, with a significant increase in FTO as the main ...
Yatan Li +6 more
wiley +1 more source
Proteomics: The Nucleolus Weighs In [PDF]
Current Biology, 2002 Numerous studies have indicated that the nucleolus is involved in a variety of cellular processes besides its well-known function in ribosome biosynthesis. A recent study describing the nucleolar proteome opens the way to new avenues of research on this important nuclear suborganelle.
A. Gregory Matera, Jason K. Ospina
openaire +3 more sources
Angewandte Chemie International Edition, EarlyView.Bioreversible Arginine Modification of amine‐containing protein residues (termed BioRAM) allows the serum‐compatible, readily accessible, and efficient delivery of native proteins into live cells. Combined with cell‐penetrating peptide (CPP) additives, BioRAM results in intracellular RNase A activity at nanomolar concentrations, thus enabling the ...
Jonathan Franke +3 more
wiley +1 more source