Results 151 to 160 of about 48,033 (274)

Catalysis by a Metastable Photoswitchable Cage

Angewandte Chemie International Edition, EarlyView.
A self‐assembled heteroleptic cage is formed by isomerizing a photoswitchable ligand to its metastable Z‐isomeric form (Z‐1) using green light and combining with a non‐switchable ligand (2) and palladium(II) ions. The metastable [Pd2(Z‐1)2(2)2]4+ cage is an out‐of‐equilibrium self‐assembled catalyst, and can be reversibly assembled and disassembled ...
Simona S. Capomolla, Christopher M. Leonhardt, Samina Rasheed, Jake P. Violi, William A. Donald, Paul J. Lusby, Jonathon E. Beves   +6 more
wiley   +1 more source

Protein-confined imidazolium intermediates enable diverse biocatalytic C-C and C-N bond formations. [PDF]

Nat Catal
Birch-Price Z, Hutton AE, Zhao F, Ortmayer M, Stoianova V, Merten C, Levy C, Obexer R, Green AP.   +8 more
europepmc   +1 more source

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

Angewandte Chemie International Edition, EarlyView.
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source

S-Nitrosothiols as Thiol-Protecting Groups for Controlled Thiol-Maleimide Crosslinking of Homogeneous Soft Hydrogels. [PDF]

Adv Mater
Serna JA, Iwohn MJ, Seifermann M, Heißler S, Schliephake M, Dopp F, Muhle-Goll C, Levkin PA.   +7 more
europepmc   +1 more source

Chiral methyl trans-2,2-dichloro-3-methylcyclopropanecarboxylate upon exposure to thiophenolate nucleophile

ARKIVOC, 2013
Vitaly N. Kovalenko
doaj   +1 more source

How Do DICER1 Syndrome Mutations Disrupt Catalysis? Unveiling Dicer Metal Binding Architecture and Mechanism of Action Using MD Simulations and QM/MM Calculations. [PDF]

J Comput Chem
Nikkel DJ, Wetmore SD.
europepmc   +1 more source

Stereoselectivity of Galactosylation Reactions In Vacuo. [PDF]

J Am Chem Soc
Chang CW, Zviagin A, Wehner D, Geue N, Jordan JS, Zidar A, Wieseke AR, Greis K, Vos GM, Götze M, Boyarkin O, Pagel K.   +11 more
europepmc   +1 more source

Discovery of the Cyclic Form of MRI pH‐Sensor Z‐OMPD Enables >5% 13C Hyperpolarization by SABRE

Angewandte Chemie International Edition, EarlyView.
With “c‐OMPD”, we discovered a previously unknown 5‐membered lactol structure that arises from the homoaldol condensation of the central metabolite pyruvic acid. We demonstrate that the cyclization equilibrium is of crucial importance for OMPD's function as MRI‐based pH sensor and achieve for the first time 13C polarization levels (>5%) by SABRE in the
Juanita Ferreira, Ivan A. Trofimov, Martin Grashei, Adriana Sacristán‐Martín, Alexander Huber, David Schleicher, Oleksiy Khavryuchenko, Franz Schilling, Andreas B. Schmidt, Max von Delius   +9 more
wiley   +1 more source

Mapping Regioisomer-Dependent Buchwald-Hartwig C-N Coupling: Bromoimidazo[1,5-a]pyridines as a Model Electrophile Series. [PDF]

Molecules
Sotnik SO, Stetsenko SV, Pavliei IM, Brusylovets OA, Pokholenko OA, Grabchuk GP, Pashenko OY, Volochnyuk DM, Ryabukhin SV.   +8 more
europepmc   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

Angewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer, Kathrin Halter, Chun‐Yin Chan, Thomas Carell   +3 more
wiley   +1 more source