Results 161 to 170 of about 48,033 (274)

Solvent Molecule-Induced Competitive Ion-Molecule Nucleophilic Substitution Reactions Involving an α‑Nucleophilic Reagent. [PDF]

ACS Omega
Fu G, Zhao S, Wang H, Liang S, Zhang J, Bai X, Zhu J, Nasen B, Liang Q, Yang L.   +9 more
europepmc   +1 more source

Design principles for vitrimers: Linking dynamic covalent chemistry, network architecture, and engineering performance

Bulletin of the Korean Chemical Society, EarlyView.
This review examines vitrimer performance from a broader perspective, considering not only dynamic covalent chemistry but also molecular structure, network architecture, and rheological behavior. These factors are discussed in relation to service and processing windows, reprocessing, repair, and engineering applications, providing a multiscale ...
Kyosun Ku, Hyeonuk Yeo
wiley   +1 more source

Access to N-Fused Acyl Aziridines for Modular Difunctionalization of Olefins by Ruthenium-Catalyzed Nitrenoid Transfer. [PDF]

Angew Chem Int Ed Engl
Kim Y, Kim S, Jung H, Kim D, Chang S.
europepmc   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source

Cyclic sulfone ring remodeling enables molecular shape diversity-oriented synthesis of privileged biaryl and oligoaryl motifs. [PDF]

Nat Commun
Nguyen VD, Nand S, Trevino R, Porey A, Thompson WT, Haug GC, Fremin SO, Dhakal SK, Hughes WB, Moran DP, Lakey-Beitia J, Giri CK, Manning-Lorino P, Greco SG, Arman HD, Larionov OV.   +15 more
europepmc   +1 more source

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

Chemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil, Bruno Di Geronimo, Toma Kashima, Akihiro Ishiwata, Katsunori Tanaka, Kiyotaka Fujita, Shinya Fushinobu, Pedro A. Sánchez‐Murcia   +7 more
wiley   +1 more source

A Pyridoxal 5'-Phosphate-Dependent Decarboxylative Mannich Reaction Initiates Construction of the Nonpeptidic Scaffold of Kaitocephalin. [PDF]

J Am Chem Soc
Noguchi T, Maeno Y, Furihata K, Shin-Ya K, Kuzuyama T.   +4 more
europepmc   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Actions of Pharmaceutical Lactones and Lactams on the Enzymes with Lactonase Activity: In Silico Prediction and In Vitro Study. [PDF]

Int J Mol Sci
Efremenko E, Domnin M, Sarapina A, Zagidulina A.   +3 more
europepmc   +1 more source

Two‐Coordinate 13‐Electron PdI Complexes Stabilized by the Bulky DIMeIHeptCl NHC Ligand

Chemistry – A European Journal, EarlyView.
Bulky N‐heterocyclic carbene (NHC) ligand DiMeIHeptCl stabilizes rare two‐coordinate 13‐electron PdI species. These monomeric complexes are directly observed crystallographically and by electron paramagnetic resonance (EPR) spectroscopy, and display unusual structures and radical‐type reactivity, forming Pd0(NHC) via Pd─X bond homolysis or ...
Volodymyr Semeniuchenko, Sepideh Sharif, Neha Rana, Nalin Chandrasoma, Wilfried M. Braje, R. Tom Baker, Jeffrey M. Manthorpe, William J. Pietro, Michael G. Organ   +8 more
wiley   +1 more source