A Functional Protein Chip for Combinatorial Pathway Optimization and In Vitro Metabolic Engineering [PDF]
, 2004 Pathway optimization is, in general, a very demanding task due to the complex, nonlinear and largely unknown interactions of enzymes, regulators and metabolites.
Jung, Gyoo Yeol, Stephanopoulos, Gregory
core
Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]
, 2018 Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel +2 more
core
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation. [PDF]
Sci Signal, 2021 Ernst O +21 more
europepmc +1 more source
Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency. [PDF]
Int J Mol Sci, 2020 Chatterjee A +6 more
europepmc +1 more source
Progress on Nme (NDP kinase/Nm23/awd) gene family-related functions derived from animal model systems: Studies on development, cardiovascular disease, and cancer metastasis exemplified [PDF]
, 2015 Hsu, T +3 more
core +1 more source
Preparative Synthesis of dTDP-L-Rhamnose Through Combined Enzymatic Pathways
, 2005 dTDP-L-rhamnose, an important precursor of O-antigen, was prepared on a large scale from dTMP by executing an one-pot reaction in which six enzymes are involved. Two enzymes, dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase and dTDP-4-keto-rhamnose reductase,
Kang, Young Bok Abraham +7 more
core
Identification and mechanism of key genes in inflammatory response of chronic otitis media in rats
Scientific ReportsChronic suppurative otitis media (CSOM) affects 330 million people globally; however, biomarkers for its inflammatory response (IR) remain underinvestigated. This study aimed to identify key genes in IR and explore the mechanisms of CSOM.
Oulai Li +5 more
doaj +1 more source
Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy. [PDF]
J Clin Med, 2020 Buljubasic F +16 more
europepmc +1 more source
Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. [PDF]
J Bacteriol, 2019 Kapoor I, Emam EAF, Shaw A, Varshney U.
europepmc +1 more source