Results 121 to 130 of about 146,762 (298)

SYNTHETIC NUCLEOSIDES

, 1925
P.A. Levene, Harry Sobotka
openalex   +1 more source

Mechanical unloading is accompanied by reverse metabolic remodelling in the failing heart: Identification of a novel citraconate‐mediated pathway

European Journal of Heart Failure, EarlyView.
Aims Although functional recovery of the failing heart with left ventricular assist device (LVAD) unloading can occur, the underpinning mechanism is unclear. We aimed to characterize the effect of myocardial biochemical effect of LVAD support in vivo and in vitro.
David M. Kaye, Xiao Suo Wang, Yen Chin Koay, Mengbo Li, Bailey McIntosh, Yann Huey Ng, Michael Rahman, Yiyang Cao, Francine Z. Marques, Cassandra Malecki, Shane Nanayakkara, Justin Mariani, Bing Wang, Sean Lal, Giovanni Guglielmi, John F. O'Sullivan   +15 more
wiley   +1 more source

New Glycoconjugates Containing Selenium and Polyphenols. Stereoselective Synthesis by Pummerer‐like Rearrangement.

European Journal of Organic Chemistry, EarlyView.
Two series of novel six‐membered Se‐glycoconjugates containing hydroxycinnamic acids marked by well‐known antioxidant properties are synthesized, exploiting a Mitsunobu reaction and a Pummerer‐like rearrangement. A first example of six‐membered selenosugar with selenium in the ring and bearing an acetal‐like functional group at C‐1 was reported, which ...
Claudia González, Mauro De Nisco, Reinier Lemos, Giovanna Cimmino, Yoana Pérez‐Badell, Severina Pacifico, Silvana Pedatella   +6 more
wiley   +1 more source

THE UTILIZATION OF PURINE NUCLEOSIDES FOR NUCLEIC ACID SYNTHESIS IN THE RAT

, 1952
Bertram A. Lowy, John Davoll, George Bosworth Brown   +2 more
openalex   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

ELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

SOME CHEMICAL PROPERTIES OF DESOXYRIBOSE NUCLEOSIDES

, 1951
Lionel A. Manson, J. O. Lampen
openalex   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

NUCLEOSIDE TRIPHOSPHATE POOLS AND THE REGULATION OF RNA SYNTHESIS IN E. coli [PDF]

, 1969
Gordon Edlin, Gunther S. Stent
openalex   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

Nucleoside diphosphate sugars and saccharide synthesis [PDF]

, 1964
LF Leloir
openalex   +1 more source