Results 201 to 210 of about 173,532 (309)

Screening of purine nucleoside analogues against intracellular Toxoplasma gondii. [PDF]

Int J Parasitol Drugs Drug Resist
Elati HAA, Van Calenbergh S, Sheiner L, de Koning HP.   +3 more
europepmc   +1 more source

Dealing With Conflicts in Medical Decisions: Epistemic Reasonable Disagreement Between Parents and Medical Staff

Bioethics, EarlyView.
ABSTRACT Many controversies in medical ethics, particularly those involving conflicts between parents and medical staff over decisions about child patients, are challenging to manage without causing significant polarization and communication issues. This is primarily because the parties involved—parents and physicians—operate at different epistemic ...
Chiara Innorta
wiley   +1 more source

Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues. [PDF]

NPJ Antimicrob Resist
Alav I, Ashraf A, Pordelkhaki P, Buckner MMC.   +3 more
europepmc   +1 more source

Correction to 'Decoding nucleoside supplementation: how thymidine outperforms ribonucleosides in accelerating mammalian replication forks'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Negatively Charged Pronucleotides as Inhibitors of Glioma Cell Proliferation. [PDF]

ACS Med Chem Lett
Romanowska J, Wawrzyniak D, Szymanska-Michalak A, Framski G, Pawlowicz-Perczak A, Sobkowski M, Stawinski J, Rolle K, Kraszewski A.   +8 more
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Metabolomics of Ocular Tissues with High and Low Metabolic Activity. [PDF]

Metabolites
Greiner JV, Glonek T.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Enhancing the Nucleoside Analog Response with Translational Therapeutic Approaches to Overcome Resistance. [PDF]

Cells
Thibodeau J, Hershberger K, Ramakrishna SSM, Su Y, Timmer L, Brophy B, Zhang K, Edwards H, Taub JW, Ge Y.   +9 more
europepmc   +1 more source