Results 191 to 200 of about 149,829 (255)

A systematic review of evidence on weight change following initiation of long‐acting cabotegravir for the prevention or treatment of HIV

open access: yesHIV Medicine, EarlyView.
Abstract Background Weight gain is an increasingly recognized concern among people receiving antiretroviral therapy (ART) and may increase the risk of non‐communicable diseases. Integrase inhibitors (INSTIs) such as dolutegravir (DTG) have been associated with weight gain, but the metabolic effects of long‐acting cabotegravir (CAB‐LA), another INSTI ...
Jonathan Kitonsa   +8 more
wiley   +1 more source

Chronic alanine aminotransferase elevation in people with HIV: Time trends over 22 years and genetic predisposition

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Chronic elevation of alanine aminotransferase (cALT) is common in people with HIV. Published reports on cALT prevalence time trends have not been uniform. It is unknown whether genetic background is associated with cALT in people with HIV. Methods cALT was defined as ALT levels (male, >50 U/L, female, >35 U/L) at ≥2 consecutive, 6‐
Noemi R. Simon   +72 more
wiley   +1 more source

Genome‐scale insights into metabolic streamlining and photosynthetic energy balance in the extremophile green alga Picocystis salinarum (Picocystophyceae, Chlorophyta)

open access: yesJournal of Phycology, EarlyView.
Abstract Picocystis salinarum is an early‐diverging chlorophyte and the sole described member of the Picocystophyceae, frequently dominating hypersaline and alkaline lakes despite extreme physicochemical constraints. To elucidate the genomic foundations of its ecological success, we generated a fully annotated, chromosome‐scale nuclear genome assembly ...
Claude Lemieux   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

Apoplast multi‐omics profiling during fungal infection uncovers new players of basal and early induced immunity in Arabidopsis thaliana

open access: yesNew Phytologist, EarlyView.
Important processes taking place in the apoplast during plant–pathogen interaction identified by multi‐omics profiling of the apoplastic fluid. Summary The extracellular space in plant tissues, known as the apoplast, remains one of the least characterized cellular compartments.
Antoine Davière   +10 more
wiley   +1 more source

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