Results 171 to 180 of about 251,788 (307)

Microwave-assisted nucleophilic fluorination: a facile approach to the synthesis of 6',6'-<i>gem</i>-difluorinated carbocyclic nucleosides. [PDF]

Front Chem
Huang G, Li X, Cui D, Zhi W, Qi P, Hao X, Liu P.   +6 more
europepmc   +1 more source

Cell‐Free Protein Synthesis in Porous Parylene Scaffolds

Small Methods, EarlyView.
The CinPP system, embedding CFPS machineries within porous parylene, is proposed as a novel platform for in vitro protein synthesis, overcoming previous limitations related to processability, structuring integration, and storage stability. By introducing porous parylene as a replacement for aqueous medium via CVD, CinPP paves the way for expanded bio ...
Gunoh Lee, So Jeong Lee, Min‐Jung Park, Hsien‐Yeh Chen, Joerg Lahann, Dong‐Myung Kim, Kyung Jin Lee   +6 more
wiley   +1 more source

Heck-type C-glycosylations in the synthesis of artificial nucleotides and functional nucleic acids. [PDF]

RSC Chem Biol
Dörrenhaus R, Zenz A, Kath-Schorr S.
europepmc   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

NS5-targeting nucleoside analogs inhibit dengue virus and other flaviviruses. [PDF]

PLoS Pathog
Bhakt P, Pokharel SM, Li Y, Srivastava T, Miller J, Dittmar M, Zhu Y, Nguyen D, Walter Z, Ayyanathan K, Tudor M, Yu C, Chatterjee AK, Ramage H, Schultz D, Cherry S.   +15 more
europepmc   +1 more source

Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro‐Organic Synthesis

The Chemical Record, EarlyView.
Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe, Johannes Schneider, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Metabolism of Epigenetic Ribonucleosides Leads to Nucleolar Stress and Cytotoxicity. [PDF]

ACS Chem Biol
Sun X, Donlic A, Boyer JA, Press TE, Kim M, Reddy NK, Brangwynne CP, Rabinowitz JD, Kleiner RE.   +8 more
europepmc   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues. [PDF]

NPJ Antimicrob Resist
Alav I, Ashraf A, Pordelkhaki P, Buckner MMC.   +3 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source