Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Benzozithiol-2-yl as a New Hydroxyl Protecting Group in Nucleosides
Mitsuo Sekine, T. HATA
openalex +1 more source
A one step synthetic approach to L-pyrimidine nucleosides using Natural Phosphate coated with potassium iodide as catalyst [PDF]
Hassan B. Lazrek +4 more
openalex +1 more source
ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont +9 more
wiley +1 more source
Microwave-assisted nucleophilic fluorination: a facile approach to the synthesis of 6',6'-<i>gem</i>-difluorinated carbocyclic nucleosides. [PDF]
Huang G +6 more
europepmc +1 more source
Development of an Improved Assay for Purine Nucleoside Kinase Activity in Cell Extracts and Detection of Inosine Kinase Activity inBrevibacterium acetylicumATCC 953, Related Species, andCorynebacterium flaccumfaciensATCC 6887 [PDF]
Hisashi Kawasaki +3 more
openalex +1 more source
Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul +8 more
wiley +1 more source
Heck-type C-glycosylations in the synthesis of artificial nucleotides and functional nucleic acids. [PDF]
Dörrenhaus R, Zenz A, Kath-Schorr S.
europepmc +1 more source
Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez +3 more
wiley +1 more source
Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues. [PDF]
Alav I +3 more
europepmc +1 more source

