Results 251 to 260 of about 339,632 (390)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Drug resistance mutations and phylogenetic analysis of HIV-1 subtypes B and F from mothers and children with vertical transmission. [PDF]

BMC Infect Dis
Luz AL, Lima K, Leal É, Pessôa FS, de Oliveira Ribeiro G, de Andrade Arrais Rosa CR, de Sousa MDG, Farias PCS, Lacerda HR.   +8 more
europepmc   +1 more source

Synthetic Nucleosides and Nucleotides. III. On the Syntheses of Several 2, 6, 8-Trisubstituted Purine Ribonucleosides

, 1968
Mineo Saneyoshi
openalex   +2 more sources

Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals

Small Methods, EarlyView.
Many organisms self‐organize crystals for vision, pigmentation, or storage. In zebrafish, iridophores produce anisotropic crystals in iridosomes. Using imaging and genetic tools, crystal growth is shown to favor the b‐axis, shaped by guanine‐to‐hypoxanthine ratios and hydrogen bonding resulting thereof.
Jannik Rothkegel, Sylvia Kaufmann, Michaela Wilsch‐Bräuninger, Catarina Lopes, Rita Mateus   +4 more
wiley   +1 more source

Synthesis of Pyrrole Nucleosides by the Photo-dehydrogenation ofΔ³-Pyrroline Derivatives [PDF]

, 1969
Masajiro Kawana, Sakae Emoto
openalex   +1 more source

OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.

Cancer Research, 2017
C. Drenberg, A. Gibson, S. Pounds, Lei Shi, Dena P Rhinehart, Lie Li, Shuiying Hu, G. Du, A. Nies, M. Schwab, Navjotsingh Pabla, W. Blum, T. Gruber, S. Baker, A. Sparreboom   +14 more
semanticscholar   +1 more source

Acoustically Responsive Nanofibrous Scaffolds with 3D Hierarchy for Tympanic Membrane Regeneration

Small Structures, EarlyView.
This study investigates the influence of molecular, hierarchical, and acoustical stimulation on biofabricated tympanic membrane (TM) scaffolds within a custom‐built bioreactor mimicking the native tissue niche. It demonstrates that synergistically integrated bioactive agents, 3D hierarchical patterns, and sound waves promote the formation of an aligned
Shivesh Anand, Claudia Del Toro Runzer, Elizabeth Rosado Balmayor, Martijn van Griensven, Lorenzo Moroni, Carlos Mota   +5 more
wiley   +1 more source

Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys. [PDF]

Nat Commun
Pitts J, Zamora JLR, Manhas S, Aeschbacher T, Chan J, Cutillas V, Nair V, Riola NC, Vijjapurapu A, Vermillion MS, Eng S, Richards C, Han D, Perry JK, Chaudhuri S, Liu SW, Martinez C, Peinovich N, Sun KH, Cai A, Martin R, Moshiri J, Hedskog C, Babusis D, Siegel DS, Kalla R, Avadhanula V, Piedra PA, Stobbelaar K, Delputte PL, Marceau C, Mateo R, Maiorova E, Mo H, Subramanian R, Mackman RL, Cihlar T, Fletcher SP, Bilello JP.   +38 more
europepmc   +1 more source

Studies of Nucleosides and Nucleotides. XXV. Purine Cyclonucleosides. 2. Synthesis of 5'-Deoxyguanosine via an 5', 8-Cyclonucleoside

, 1965
Morio Ikehara, Hiroshi Tada, Kei Muneyama   +2 more
openalex   +2 more sources

Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.
Vladyslav Dovhalyuk, Fan Yang, Sara Nikolic, Miroslav Vujasinovic, J.‐Matthias Löhr, Daniel Globisch   +5 more
wiley   +1 more source