Results 321 to 330 of about 235,474 (365)

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

Chemical reactivity of RNA and its modifications with hydrazine. [PDF]

Commun Chem
Yeşiltaç-Tosun N, Qi Y, Li C, Stafflinger H, Hollnagel K, Rusling L, Wöhnert J, Kaiser S, Kaiser S.   +8 more
europepmc   +1 more source

Single-molecule detection of oligonucleotides using the fluorescent nucleobase analogue ABN. [PDF]

Chem Sci
Samaan GN, Jimenez Salinas A, Bailie AE, Grim J, Cizmic JM, Jones AC, Lee Y, Purse BW.   +7 more
europepmc   +1 more source

Three-Year Effectiveness of Bictegravir/Emtricitabine/Tenofovir Alafenamide as a Switch Strategy in the Real World. [PDF]

Open Forum Infect Dis
de Gea-Grela A, Micán R, de Miguel R, Serrano L, Marcelo C, Montes ML, Ramos-Ruperto L, Busca C, Arcos-Rueda MDM, Montejano R, Arribas JR, Gonzalez-García J, Bernardino JI, Martín-Carbonero L.   +13 more
europepmc   +1 more source

Discovery of Novel Pyrido[2,3-b]Pyrazine Human Cytomegalovirus Polymerase Inhibitors with Broad Spectrum Antiherpetic Activity and Reduced hERG Inhibition. [PDF]

ChemMedChem
Bai B, Srinivas Kandadai A, Hena M, Belovodskiy A, Shen J, Houghton M, Nieman JA.   +6 more
europepmc   +1 more source

Unraveling the full impact of SPD_0739: a key effector in S. pneumoniae iron homeostasis. [PDF]

Microbiol Spectr
Womack E, Antone M, Eichenbaum Z.
europepmc   +1 more source

Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides. [PDF]

Elife
Fu Y, Luo XD, Li JZ, Mo QY, Wang X, Zhao Y, Zhang YM, Luo HT, Xia DY, Ma WQ, Chen JY, Wang LH, Deng QY, Ben L, Kashif Saleemi M, Jiang XZ, Chen J, Miao K, Lin ZP, Zhang P, Ye H, Cao QY, Zhu YW, Yang L, Tu Q, Wang W.   +25 more
europepmc   +1 more source

Ultrasensitive detection of a responsive fluorescent thymidine analogue in DNA via pulse-shaped two-photon excitation.

Phys Chem Chem Phys
Bailie AE, Sansom HG, Fisher RS, Watabe R, Tor Y, Jones AC, Magennis SW.   +6 more
europepmc   +1 more source

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Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

Pharmacology & Therapeutics, 2000
Nucleoside monophosphate kinases catalyze the reversible phosphotransferase reaction between nucleoside triphosphates and monophosphates, i.e., monophosphates are converted to their corresponding diphosphate form. These enzymes play an important role in the synthesis of nucleotides that are required for a variety of cellular metabolic processes, as ...
Anna Karlsson, Magnus Johansson, An R. Van Rompay   +2 more
openaire   +3 more sources

Nucleosides

ChemInform, 1990
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source