Results 141 to 150 of about 42,303 (291)

Data from Nucleoside Diphosphate Kinase-3 (<i>NME3</i>) Enhances TLR5-Induced NF<b>κ</b>B Activation

, 2023
Kelly Flentie, Caleb González, Brandon Kocher, Yue Wang, Hongtu Zhu, Jayne Marasa, David Piwnica‐Worms   +6 more
openalex   +1 more source

Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase*

Journal of Biological Chemistry, 2012
Background: AMPK phosphorylates CFTR and inhibits PKA-stimulated CFTR channel gating by unclear mechanisms. Results: NDPK-A, AMPK, and CFTR exist in a membrane-associated complex.
J. D. King, Jeffrey K. Lee, C. Riemen, D. Neumann, Sheng Xiong, Sheng Xiong, J. K. Foskett, A. Mehta, R. Muimo, K. Hallows   +9 more
semanticscholar   +1 more source

Mycoplasmas and cancer [PDF]

, 2014
The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan, Liekens, Sandra, Vande Voorde, Johan   +2 more
core  

Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity

mBio
Guanosine triphosphate (GTP) is essential for macromolecular biosynthesis, and its intracellular levels are tightly regulated in bacteria. Loss of the alarmone (p)ppGpp disrupts GTP regulation in Bacillus subtilis, causing cell death in the presence of ...
Fukang She, Kuanqing Liu, Brent W. Anderson, Tippapha Pisithkul, Yanxiu Li, Danny K. Fung, Tyler McCue, William Mulhern, Daniel Amador-Noguez, Jue D. Wang   +9 more
doaj   +1 more source

Nucleoside diphosphate kinase of Saccharomyces cerevisiae, Ynk1p: localization to the mitochondrial intermembrane space [PDF]

, 2003
Boominathan Amutha, Debkumar Pain
openalex   +1 more source

Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1

eLife, 2016
KCa2.1, KCa2.2, KCa2.3 and KCa3.1 constitute a family of mammalian small- to intermediate-conductance potassium channels that are activated by calcium-calmodulin.
Shekhar Srivastava, Saswati Panda, Zhai Li, Stephen R Fuhs, Tony Hunter, Dennis J Thiele, Stevan R Hubbard, Edward Y Skolnik   +7 more
doaj   +1 more source

Nucleoside Diphosphate Kinase and Flagellin from Pseudomonas aeruginosa Induce Interleukin 1 Expression via the Akt/NF-κB Signaling Pathways [PDF]

, 2014
Yong‐Jae Kim, Jung‐Hoon Lee, Yeji Lee, Jingyue Jia, Se‐Hwan Paek, Hyong-Bai Kim, Shouguang Jin, Un‐Hwan Ha   +7 more
openalex   +1 more source

A Functional Protein Chip for Combinatorial Pathway Optimization and In Vitro Metabolic Engineering [PDF]

, 2004
Pathway optimization is, in general, a very demanding task due to the complex, nonlinear and largely unknown interactions of enzymes, regulators and metabolites.
Jung, Gyoo Yeol, Stephanopoulos, Gregory
core  

Activation of G-proteins by receptor-stimulated nucleoside diphosphate kinase in Dictyostelium. [PDF]

, 1993
Anthony A. Bominaar, Anco Molijn, Martine Pestel, M. Véron, P J Van Haastert   +4 more
openalex   +1 more source

Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]

, 2018
Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel, Giai, Constanza, Zarelli, Valeria Eugenia Paola   +2 more
core