Results 101 to 110 of about 49,657 (223)

Incidence of lipodystrophy and metabolic disorders in patients starting non-nucleoside reverse transcriptase inhibitors in Benin [PDF]

, 2008
Djimon Marcel Zannou, Lise Denoeud‐Ndam, Karine Lacombe, Daniel Amoussou-Guénou, Jules Bashi, Jocelyn Akakpo, Alice Gougounon, Alain Akondé, Gabriel Adè, Fabien Houngbé, Pierre‐Marie Girard   +10 more
openalex   +1 more source

Efficacy and safety of darunavir and etravirine in a patient with retroviruses and multiple virologic failure

Clinical Management Issues, 2009
Drug resistance to antiretroviral regimen is a challenging problem in HIV-infected patients. We describe a case of a 45-year-old Caucasian male that, after failure of several successive antiretroviral regimens, has been successfully treated with a ...
Claudia Bernardini, Raffaella Rosso
doaj   +1 more source

Efficacy of 1998 vs 2006 first-line antiretroviral regimens for HIV infection: an ordinary clinics retrospective investigation [PDF]

, 2012
Purpose: The evidence suggesting increased HAART efficacy over time comes from randomized trials or cohort studies. This retrospective multicenter survey aimed to assess the variation over time in the efficacy and tolerability of first-line HAART ...
Antinori, Andrea, Bonfanti, Paolo, Celesia, Benedetto Maurizio, Dalessandro, Margherita, De Socio, Giuseppe Vittorio Luigi, Di Masi, Francesco, Madeddu, Giordano, Manzoli, Lamberto, Marconi, Patrizia, Martinelli, Canio, Mazzotta, Elena, Mura, Maria Stella Anna, Nigro, Luciano, Parruti, Giustino, Pellicanò, Giovanni, Polilli, Ennio, Ricci, Elena, Soddu, Viviana, Sozio, Federica, Ursini, Tamara, Vecchiet, Jacopo, Vitiello, Paola   +21 more
core  

Combination antiretroviral therapy -associated lipodystrophy : insights into pathogenesis and treatment [PDF]

, 2011
Introduction: Combination antiretroviral therapy (cART) has decreased morbidity and mortality of individuals infected with human immunodeficiency virus type 1 (HIV-1). Its use, however, is associated with adverse effects which increase the patients risk
Sevastianova, Ksenia
core  

Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

Viruses, 2010
HIV-1 Reverse Transcriptase (HIV-1 RT) has been the target of numerous approved anti-AIDS drugs that are key components of Highly Active Anti-Retroviral Therapies (HAART).
Stefan G. Sarafianos, Eleftherios Michailidis, Karen A. Kirby, Bruno Marchand, Kamalendra Singh   +4 more
doaj   +1 more source

N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. [PDF]

J Med Chem, 2023
Lane T, Makarov V, Nelson JAE, Meeker RB, Sanna G, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Urbina F, Jones T, Suchy A, Ekins S.   +12 more
europepmc   +1 more source

Full-Spectrum Surveillance of Pre-Treatment HIV Drug Resistance in Southeastern China

Pharmaceuticals
HIV drug resistance compromises the ability of anti-retroviral therapy (ART) to suppress viral replication, resulting in treatment failure. This study investigates the prevalence of pre-treatment drug resistance (PDR) in newly diagnosed individuals in a ...
Jiafeng Zhang, Baochang Sun, Zihang Sheng, Xiaobei Ding, Qin Fan, Gang Huang, Zhihong Guo, Ping Zhong, Lingjie Liao, Hui Xing, Yan Xia, Chengliang Chai, Jianmin Jiang   +12 more
doaj   +1 more source

APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants. [PDF]

Front Virol, 2022
Dwivedi R, Wang Y, Kline C, Fischer DK, Ambrose Z.   +4 more
europepmc   +1 more source

Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV. [PDF]

J Hepatol, 2021
Higashi-Kuwata N, Hayashi S, Kumamoto H, Ogata-Aoki H, Das D, Venzon D, Hattori SI, Bulut H, Hashimoto M, Otagiri M, Takamune N, Kishimoto N, Davis DA, Misumi S, Kakuni M, Tanaka Y, Mitsuya H.   +16 more
europepmc   +1 more source

Adverse perinatal outcomes associated with prenatal exposure to protease-inhibitor-based versus non-nucleoside reverse transcriptase inhibitor-based antiretroviral combinations in pregnant women with HIV infection: a systematic review and meta-analysis. [PDF]

BMC Pregnancy Childbirth, 2023
Saint-Lary L, Benevent J, Damase-Michel C, Vayssière C, Leroy V, Sommet A.   +5 more
europepmc   +1 more source