Pharmacotherapy for Cirrhosis in Japan
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley +1 more source
Production, Isolation, and Characterization of Stable Isotope-Labeled Standards for Mass Spectrometric Measurements of Oxidatively-Damaged Nucleosides in RNA. [PDF]
Jaruga P, Kant M, Dizdaroglu M.
europepmc +1 more source
NUCLEOSIDE PHOSPHATASE ACTIVITIES IN RAT CARDIAC MUSCLE [PDF]
Edward Essner+2 more
openalex +1 more source
Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá+4 more
wiley +1 more source
Photoredox-Catalyzed Site-Selective Intermolecular C(sp3)-H Alkylation of Tetrahydrofurfuryl Alcohol Derivatives. [PDF]
Abe R+5 more
europepmc +1 more source
A Microsomal Nucleoside Diphosphatase
Alex B. Novikoff, Margareta Heus
openalex +1 more source
ENT‐1‐Targeted Polymersomes to Enhance the Efficacy of Methotrexate in Choriocarcinoma Treatment
ENT‐1‐targeted stimuli‐responsive polymersomes enhance the delivery and release of MTX, as demonstrated in choriocarcinoma tumors mouse model. These targeted nanocarriers improve tumor uptake and efficiently release the drug within the tumor, highlighting their potential for enhanced chemotherapy in choriocarcinoma treatment.
Babak Mamnoon+10 more
wiley +1 more source
Genome Analysis and In Vitro Assay of Probiotic Properties of <i>Bacillus paranthracis</i> YC03 with Urate-Lowering Potential. [PDF]
Cao X, Zhang Y, Xu Q, Yan H.
europepmc +1 more source
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos+2 more
wiley +1 more source
NupR Is Involved in the Control of PlcR: A Pleiotropic Regulator of Extracellular Virulence Factors. [PDF]
Qin J+7 more
europepmc +1 more source