Results 281 to 290 of about 198,787 (385)

Recent Synthetic Advances in C–H/N–H Functionalization of 1H‐Pyrazoles: Diverse Strategies Across Variously Substituted Scaffolds

The Chemical Record, EarlyView.
Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür, Asta Žukauskaitė, Algirdas Šačkus, Eglė Arbačiauskienė   +3 more
wiley   +1 more source

Gold Mono- and Bis-N-heterocyclic Carbenes Based on mRNA cap0. [PDF]

ACS Omega
Francescato G, Orsini G, Petronilho A.
europepmc   +1 more source

Precise Measurement of the G+C Content of Deoxyribonucleic Acid by High-Performance Liquid Chromatography

, 1989
M. Mesbah, U. Premachandran, W. Whitman
semanticscholar   +1 more source

Pay up or die: Tradeoffs between costly telomere maintenance, somatic growth and body condition in embryonic and adult sand lizards

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Current knowledge about telomere biology relies to a very high degree on results from research on endotherms. This would not be problematic if organisms shared the same mechanisms regulating telomere length (TL) but this is not necessarily the case; for example, most ...
Mats Olsson, Emily Miller, Nicky Rollings, Erik Wapstra   +3 more
wiley   +1 more source

5'-Guanidino Xylofuranosyl Nucleosides as Novel Types of 5'-Functionalized Nucleosides with Biological Potential. [PDF]

Pharmaceuticals (Basel)
Szilagyi J, Moreira T, Nunes RS, Silva J, Alves C, Martins A, Alvariño R, Heise NV, Csuk R, Xavier NM.   +9 more
europepmc   +1 more source

Studies of Nucleosides and Nucleotides. XXXIX. Synthesis of 8-Substituted Purine Nucleotides by the Direct Replacement Reactions

, 1969
Morio Ikehara, Ichiro Tazawa, Toshikazu Fukui   +2 more
openalex   +2 more sources

Aging Reduces Intestinal Stem Cell Activity in Killifish and Intermittent Fasting Reverses Intestinal Gene Expression Patterns

Aging Cell, EarlyView.
Intestinal stem cells occur in clusters, and the cycle time of stem cells increases with age. The age‐dependent decline in structural intestinal tissue homeostasis is associated with a decline in stem cell activity. Aging causes significant changes in intestinal gene expression; intermittent fasting from adulthood onwards results in a gene expression ...
Michael Kothmayer, Sylvia Laffer, Philipp Widmayer, Elmar E. Ebner, Fehima Ugarak, David Martin, Stefan H. Geyer, Kareem Elsayad, Wolfgang J. Weninger, Sabine Lagger, Klara Weipoltshammer, Oliver Pusch, Christian Schöfer   +12 more
wiley   +1 more source

On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines. [PDF]

Cells
Mohl DA, Lagies S, Lonzer A, Pfäffle SP, Groß P, Benka M, Jäger M, Huber MC, Günther S, Plattner DA, Juhasz-Böss I, Backhaus C, Kammerer B.   +12 more
europepmc   +1 more source

Studies on Nucleosides and Nucleotides. VII-VIII. VIII. A N ew Method for Synthesis of Purine-Ribonucleosides, . Part. 2

, 1960
Tetsuo Sato, Tosisada SIMADATE, Yoshiharu Ishido   +2 more
openalex   +2 more sources

Telomerase modRNA Offers a Novel RNA‐Based Approach to Treat Human Pulmonary Fibrosis

Aging Cell, EarlyView.
Recombinant linear and circular hTERT mRNA restore telomerase activity in primary ATII cells and ex vivo lung tissue from patients with pulmonary fibrosis, leading to telomere elongation, reduced DNA damage, and decreased senescence and fibrosis markers.
Jia Li Ye, Klaudia Grieger, Dongchao Lu, Christina Brandenberger, Malte Juchem, Maria Jordan, Lea Oehlsen, Patrick Zardo, Christopher Werlein, Christina Hesse, Katherina Sewald, Sandy Tretbar, Thomas Thum, Shambhabi Chatterjee, Christian Bär   +14 more
wiley   +1 more source