Results 301 to 310 of about 197,362 (384)

Precision oncology to overcome resistance in R/R AML in children and adults requires combinations of cytotoxic, targeted, and immunological treatments

Journal of Internal Medicine, EarlyView.
Abstract Although outcomes for newly diagnosed acute myeloid leukaemia (AML) have been incrementally improved over the last decades, management of relapsed and refractory (R/R) AML remains a medical challenge. A curative intent for R/R AML usually involves chemotherapy (with or without targeted therapy) with subsequent consolidation, including ...
Martin Jädersten, Ingrid Lilienthal, Christer Nilsson, Louisa Fredrikson, Cornelis Jan Pronk, Kristian Løvvik Juul‐Dam, Mika Kontro, Nikolas Herold   +7 more
wiley   +1 more source

Differentiation Trajectory of Virus‐Induced Tumour Cells in Rice Revealed by Single‐Cell RNA Sequencing

Plant Biotechnology Journal, EarlyView.
ABSTRACT Many plant viruses trigger abnormal differentiation and development of host cells, causing distinct symptoms. Here, in a single‐cell RNA sequence analysis, we find transcriptional heterogeneity between cells from rice leaf sheaths that are infected with rice black streaked dwarf virus (RBSDV) and from those that are virus‐free.
Nan Wu, Lu Gan, Qingqing Suo, Fei Yang, Wenwen Liu, Xifeng Wang, Huaibing Jin   +6 more
wiley   +1 more source

[Preparation and chromatographic performance evaluation of hydrophilic interaction chromatography stationary phase based on amino acids]. [PDF]

Se Pu
Xu GG, Yi Y, Liu PP, Zhang WF.
europepmc   +1 more source

Preparation of Organometallic Complexed Sugars:  Hetero Diels−Alder Reactivity of Tricarbonyl(formyltrimethylenemethane)- iron [PDF]

, 1997
Donaldson, William, Kleindl, Paul J.
core   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak, Michelle C. M. van Winden, Thomas V. Harwood, Rachel Neurath, Suzanne M. Kosina, Katherine B. Louie, Matthew B. Sullivan, Simon Roux, Karsten Zengler, Vivek K. Mutalik, Trent R. Northen   +10 more
wiley   +1 more source

Effects of mirror-image nucleosides on DNA replication and transcription in human cells. [PDF]

J Biol Chem
Jin Z, Wang Y, Cui S, He Y, Wu L.
europepmc   +1 more source

Associations of Nucleoside Diphosphate‐Linked Moiety X‐Type Motif 15 Variants With Neutropenia During Antiviral Therapy for Cytomegalovirus Disease in Pediatric Liver Transplant Recipients

Transplant Infectious Disease, EarlyView.
NUDT15 variants were associated with an increased risk of neutropenia in pediatric liver transplant recipients receiving GCV/VGCV treatment. Genetic screening before treatment initiation may help optimize antiviral therapy, minimize hematological toxicity, and improve patient management.
Ken‐ichi Iwata, Yuka Torii, Yuto Fukuda, Kazunori Haruta, Makoto Yamaguchi, Takako Suzuki, Yasuhiro Ogura, Jun‐ichi Kawada   +7 more
wiley   +1 more source

NMR-Based Metabolomic Approach to Study Growth of <i>Phaseolus vulgaris</i> L. Seedlings Through Leaf Application of Nanofertilizers and Biofertilizers. [PDF]

Int J Mol Sci
López-Vargas ER, Hidalgo-Martínez D, Becerra-Martínez E, Zepeda-Vallejo LG, Hernández-Guerrero CJ, Hernández-Fuentes AD, Cadenas-Pliego G, Pérez-Álvarez M.   +7 more
europepmc   +1 more source

Frequency and Characterization of Local Ocular Toxicity in Cats Treated With Topical Ophthalmic Cidofovir for Presumptive Feline Herpesvirus‐1 Infection

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To determine the frequency and clinical characteristics of local ocular adverse reactions to topical ophthalmic cidofovir administration in cats with presumptive feline herpesvirus‐1 (FHV‐1) keratoconjunctivitis. Animal Studied In total, 140 cats treated with cidofovir.
Eric C. Ledbetter, Amy J. Morgan
wiley   +1 more source

Synthesis of Adenine Nucleosides with a Reactive (<i>β</i>-Iodovinyl)sulfone or (<i>β</i>-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA. [PDF]

Molecules
Howlader AH, Fernandez R, Tsegay PS, Liu Y, Wnuk SF.   +4 more
europepmc   +1 more source