Results 181 to 190 of about 156,001 (374)

In vivo assembly of complete eukaryotic nucleosomes and (H3-H4)-only non-canonical nucleosomal particles in the model bacterium Escherichia coli

Communications Biology
As a fundamental unit for packaging genomic DNA into chromatin, the eukaryotic nucleosome core comprises a canonical octamer with two copies for each histone, H2A, H2B, H3, and H4, wrapped around with 147 base pairs of DNA.
Xiaojuan Zhou, Niubing Zhang, Jie Gong, Kaixiang Zhang, Ping Chen, Xiang Cheng, Bang-Ce Ye, Guoping Zhao, Xinyun Jing, Xuan Li   +9 more
doaj   +1 more source

Chromatin Remodelers Act Globally, Sequence Positions Nucleosomes Locally

, 2009
Peretz D. Partensky, Geeta J. Narlikar
openalex   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Parental adenovirus DNA accumulates in nucleosome-like structures in infected cells

, 1979
Valerie Tate, Lennart Philipson
openalex   +2 more sources

Assessing the exercise‐related kinetics of circulating cell‐free DNA, circulating tumour DNA, DNase I activity and cytokines in patients with solid tumours: A pilot study

Experimental Physiology, EarlyView.
Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger, Alexandra Brahmer, Tobias Ehlert, Suzan Botzenhardt, Alfonso De Falco, Birgit Enders, Patricia S. Hähnel, Achim Heintz, Carl C. Schimanski, Thomas Kindler, Perikles Simon   +10 more
wiley   +1 more source

Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes [PDF]

, 2002
Ahmed H. Hassan, Philippe Prochasson, Kristen E. Neely, Scott Galasinski, Mark Chandy, Michael J. Carrozza, Jerry L. Workman   +6 more
openalex   +1 more source

Novel therapeutic strategy targeting STMN1 using chlorambucil‐conjugated pyrrole–imidazole polyamide in small cell lung cancer

International Journal of Cancer, Volume 158, Issue 5, Page 1336-1347, 1 March 2026.
What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa, Takayoshi Watanabe, Yoichi Ohtaki, Toshikazu Bando, Hiroshi Sugiyama, Takuya Araki, Hideaki Yashima, Bilguun Erkhem‐Ochir, Haruka Okami, Gendensuren Dorjkhorloo, Ikuma Shioi, Toshiteru Nagashima, Natsuko Kawatani, Tomohiro Yazawa, Eiji Narusawa, Takayuki Kosaka, Osamu Kawashima, Mitsuhiro Kamiyoshihara, John D. Minna, Luc Girard, Ken Shirabe, Hiroki Nagase, Kimihiro Shimizu, Takehiko Yokobori   +23 more
wiley   +1 more source

General regulatory factors exert differential effects on nucleosome sliding activity of the ISW1a complex

Biological Research
Background Chromatin dynamics is deeply involved in processes that require access to DNA, such as transcriptional regulation. Among the factors involved in chromatin dynamics at gene regulatory regions are general regulatory factors (GRFs). These factors
Andrea Oyarzún-Cisterna, Cristián Gidi, Fernanda Raiqueo, Roberto Amigo, Camila Rivas, Marcela Torrejón, José L. Gutiérrez   +6 more
doaj   +1 more source

NAP1L1 accelerates activation and decreases pausing to enhance nucleosome remodeling by CSB [PDF]

, 2017
Ju Yeon Lee, Robert J. Lake, Jaewon Kirk, Vilhelm A. Bohr, Hua-Ying Fan, Sungchul Hohng   +5 more
openalex   +1 more source

‘Mini’ U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects [PDF]

, 2020
Roland Preece, Christos Georgiadis, Soragia Athina Gkazi, Annie Etuk, Abraham Christi, Waseem Qasim   +5 more
openalex   +1 more source