Results 201 to 210 of about 64,059 (299)

Echinomycin and distamycin induce rotation of nucleosome core DNA [PDF]

, 1986
C.M.Loretta Low, Horace R. Drew, Michael J. Waring   +2 more
openalex   +1 more source

CST Is Epistatic With Shieldin to Limit DNA Double‐Strand Break End Resection and Promote Repair During Igh Class Switch Recombination

European Journal of Immunology, Volume 55, Issue 4, April 2025.
Here we show that CST and SHLD are required for CSR, while SHLD1‐CTC1 interaction via the SHLD1 LDLP motif is dispensable. Mechanistically, we show that CTC1 and SHLD1 are epistatic during CSR, preventing genetic instability, exacerbated DSB end‐resection, and microhomology‐mediated end‐joining at Igh switching sites.
Chloé Lescale, Timea Marton, Amaury Vaysse, Guillaume Rode, Estelle Vincendeau, Alice Libri, François Dossin, Ludovic Deriano   +7 more
wiley   +1 more source

DNA spontaneously wrapping around a histone core prefers negative supercoiling: A Brownian dynamics study. [PDF]

PLoS Comput Biol
Long C, Liang H, Wan B.
europepmc   +1 more source

Specificity landscapes of 40 R2R3‐MYBs reveal how paralogs target different cis‐elements by homodimeric binding

iMeta, Volume 4, Issue 2, April 2025.
Closely related transcription factor (TF) paralogs are facing the “specificity paradox”—they share similar binding motifs, but their cis‐regulatory targets and physiological roles can be different. By applying high‐throughput SELEX to 40 R2R3‐MYB TFs, this study currently generates the largest data set illustrating the homodimeric specificities of ...
Tian Li, Hao Chen, Nana Ma, Dingkun Jiang, Jiacheng Wu, Xinfeng Zhang, Hao Li, Jiaqing Su, Piaojuan Chen, Qing Liu, Yuefeng Guan, Xiaoyue Zhu, Juncheng Lin, Jilin Zhang, Qin Wang, Honghong Guo, Fangjie Zhu   +16 more
wiley   +1 more source

Structural basis of SIRT7 nucleosome engagement and substrate specificity. [PDF]

Nat Commun
Moreno-Yruela C, Ekundayo BE, Foteva PN, Ni D, Calvino-Sanles E, Stahlberg H, Fierz B.   +6 more
europepmc   +1 more source

Phenotyping, genome‐wide dissection, and prediction of maize root architecture for temperate adaptability

iMeta, Volume 4, Issue 2, April 2025.
This study dissects the genetic architecture of maize Root System Architecture, identifying significant root trait differences between tropical/subtropical and temperate lines. Using genome‐wide association study, 3511 genes were linked to root morphology, weight, and slice traits.
Weijun Guo, Fanhua Wang, Jianyue Lv, Jia Yu, Yue Wu, Hada Wuriyanghan, Liang Le, Li Pu   +7 more
wiley   +1 more source

Nucleosome repositioning in cardiac reprogramming. [PDF]

PLoS One
Harris S, Baksh SS, Wang X, Anwar I, Pratt RE, Dzau VJ, Hodgkinson CP.   +6 more
europepmc   +1 more source

Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin. [PDF]

, 1992
Jennifer E. Morgan, James P. Whitlock
openalex   +1 more source

Calcium Handling Machinery and Sarcomere Assembly are Impaired Through Multipronged Mechanisms in Cancer Cytokine‐Induced Cachexia

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
Abstract Background Cachexia is a severe form of muscle wasting disorder particularly observed in patients with advanced cancer. The absence of effective strategies to ameliorate cachexia indicates our poor understanding of the mechanisms of cachexia. By employing system‐wide approaches, we investigated molecular mechanisms underlying cancer secreted ...
Luis Vincens Gand, Chiara Lanzuolo, Mugeng Li, Valentina Rosti, Natalie Weber, Dongchao Lu, Christian Bär, Thomas Thum, Andreas Pich, Theresia Kraft, Mamta Amrute‐Nayak, Arnab Nayak   +11 more
wiley   +1 more source

Site-specific Aflatoxin B1 Adduction of Sequence-positioned Nucleosome Core Particles

, 1989
Richard W. Moyer, Koenraad Marien, Kensal Van Holde, G.S. Bailey   +3 more
openalex   +1 more source