Results 201 to 210 of about 156,001 (374)
Investigating the Importance of DNA Sequence for Nucleosome Positioning with Means of Machine Learning [PDF]
Malte Sahrhage
openalex +1 more source
DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu +12 more
wiley +1 more source
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
RNA inhibits dMi-2/CHD4 Chromatin Binding and Nucleosome Remodelling
Ikram Ullah +14 more
openalex +1 more source
Understanding nucleosome dynamics and their links to gene expression and DNA replication
W. K. Lai, B. Pugh
semanticscholar +1 more source
Diagnostic and Prognostic Value of cfDNA Concentration and Fragmentation in Prostate Cancer
ABSTRACT Objective To evaluate the value of circulating free DNA (cfDNA) in prostate cancer (PCa) by cfDNA assay and analysis of plasma and urinary cfDNA fragmentation to determine the usefulness of this parameter for risk staging and tumor progression monitoring.
Marta Victoria Lorenzo‐Sánchez +8 more
wiley +1 more source
Nucleosome Recognition by the Piccolo NuA4 Histone Acetyltransferase Complex
Christopher Berndsen +5 more
openalex +1 more source
An atomic view of the NFIX–DNA complex reveals recognition of the TGGCA motif and links sequence‐specific binding to the transcriptional programs governing skeletal muscle development and disease. ABSTRACT Skeletal muscle is essential for voluntary movement and exhibits a remarkable capacity for regeneration following injury.
Ci Zhu +11 more
wiley +1 more source
Nucleosome structure and dynamics are coming of age
Keda Zhou, G. Gaullier, K. Luger
semanticscholar +1 more source
ABSTRACT Renal cell carcinoma (RCC) presents a significant global health challenge, with a substantial proportion of patients diagnosed with advanced or metastatic disease due to the limitations of current diagnostic imaging and the lack of validated non‐invasive biomarkers.
Hossam Kamli, Najeeb Ullah Khan
wiley +1 more source

