Results 61 to 70 of about 6,681 (209)

Possible roles of CD73 (ecto-5′-nucleotidase) and clinical significance in metastasis human cancer [PDF]

, 2020
Marco Antonio Lacerda‐Abreu, José Roberto Meyer‐Fernandes   +1 more
openalex   +1 more source

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1826-1835, March 2026.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone, Afroditi Tripyla, Melanie C. Scalise, Maria L. Balmer, Lia Bally, Dominik M. Meinel   +5 more
wiley   +1 more source

CD73 is a major regulator of adenosinergic signalling in mouse brain.

PLoS ONE, 2013
CD73 (ecto-5'-nucleotidase) is a cell surface enzyme that regulates purinergic signalling by desphosphorylating extracellular AMP to adenosine. 5'-nucleotidases are known to be expressed in brain, but the expression of CD73 and its putative physiological
Natalia Kulesskaya, Vootele Võikar, Marjaana Peltola, Gennady G Yegutkin, Marko Salmi, Sirpa Jalkanen, Heikki Rauvala   +6 more
doaj   +1 more source

ENTPDase inhibitors: therapeutic potential in infectious, inflammatory, and neuroinflammatory diseases [PDF]

Exploration of Neuroscience
Ectonucleoside triphosphate diphosphohydrolases (ENTPDases), members of the cluster of differentiation 39 (CD39) family, are key regulators of purinergic signaling through the hydrolysis of tri and diphosphate nucleotides.
Isadora Cunha Ribeiro, Amanda Laviola de Andrade, Vitória de Almeida Rodrigues, Markson Suarez Lacôrte Lima, Juliana Lopes Rangel Fietto   +4 more
doaj   +1 more source

Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives [PDF]

, 2021
Emma Rose Scaletti, Franziska U. Huschmann, U. Müeller, M.S. Weiss, Norbert Sträter   +4 more
openalex   +1 more source

Hypotensive Snake Venom Components—A Mini-Review

Molecules, 2019
Hypertension is considered a major public health issue due to its high prevalence and subsequent risk of cardiovascular and kidney diseases. Thus, the search for new antihypertensive compounds remains of great interest.
Orsolya Péterfi, Francisc Boda, Zoltán Szabó, Elek Ferencz, László Bába   +4 more
doaj   +1 more source

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Receptor Activation by ATP Through Rapid and Localized Generation of Adenosine by Ecto-nucleotidases

Journal of Pharmacological Sciences, 2004
Extracellular ATP is now recognized as a neurotransmitter or neuromodilator in the nervous system, producing diverse physiological effects by activating multiple P2 receptors.
Isao Matsuoka, Satoko Ohkubo
doaj   +1 more source

Mammalian 5′-Nucleotidases [PDF]

Journal of Biological Chemistry, 2003
BIANCHI, VERA, SPYCHALA J.
openaire   +3 more sources

5-Nucleotidase [PDF]

Biochemical Journal, 1938
J M, Gulland, E M, Jackson
openaire   +2 more sources

Bovine cytosolic IMP/GMP-specific 5′-nucleotidase: cloning and expression of active enzyme in Escherichia coli [PDF]

, 1997
S. Allegrini, Rossana Pesi, Maria Grazia Tozzi, J. Carol FIOL, Benjamin Johnson, Staffan Eriksson   +5 more
openalex   +1 more source