Results 81 to 90 of about 9,655 (264)

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

open access: yesZoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda   +10 more
wiley   +1 more source

Catabolism of Ap4A and Ap5A by rat brain synaptosomes

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Adenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) and adenosine 5',5'''-P1,P5-pentaphosphate (Ap5A) are stored in and released from rat brain synaptic terminals.
T. Emanuelli   +3 more
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 1078-1083, May 2026.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Neuronal NTPDase3 Mediates Extracellular ATP Degradation in Trigeminal Nociceptive Pathway.

open access: yesPLoS ONE, 2016
ATP induces pain via activation of purinergic receptors in nociceptive sensory nerves. ATP signaling is terminated by ATP hydrolysis mediated by cell surface-localized ecto-nucleotidases.
Lihua Ma   +4 more
doaj   +1 more source

Resetting intrinsic purinergic modulation of neural activity: an associative mechanism? [PDF]

open access: yes, 2002
The purines, ATP and adenosine, control the rundown and termination of swimming in the Xenopus embryo. This intrinsic purinergic modulation, unavoidably present during every swimming episode, could lead to stereotyped inflexible behavior and consequently
Dale, Nicholas
core   +1 more source

Differential Adenosine Signaling and Effects of Acute Caffeine Exposure on Alternative Stress Coping Styles in Zebrafish (Danio rerio)

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
Acute caffeine exposure exerts coping style‐ and sex‐dependent effects on anxiety‐like behavior in zebrafish, with reactive individuals, particularly males, showing the greatest sensitivity. The accompanying changes in adenosine receptor and adenosine deaminase expression demonstrate a possible molecular mechanism underlying these behavioral ...
Sydney E. Klucas, Ryan Y. Wong
wiley   +1 more source

The Immune Landscape of Acral Melanoma: From Basic to Clinical

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Acral melanoma (AM) is an aggressive melanoma subtype with poor prognosis and limited response to immune checkpoint inhibitors (ICIs). Despite increasing research efforts, the mechanisms underlying therapeutic resistance remain incompletely understood.
Lihong Jiang, Zhaotian Zhang
wiley   +1 more source

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

open access: yes, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Wall, Mark J.   +2 more
core   +2 more sources

Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu   +4 more
wiley   +1 more source

Biochemical Characterization of Nucleotidase in some Parasites [PDF]

open access: gold, 2020
Ilham AL-Tikrity   +3 more
openalex   +1 more source

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