Results 61 to 70 of about 3,609 (205)
Metabolic Aspects of Adenosine Functions in the Brain
Frontiers in Pharmacology, 2021 Adenosine, acting both through G-protein coupled adenosine receptors and intracellularly, plays a complex role in multiple physiological and pathophysiological processes by modulating neuronal plasticity, astrocytic activity, learning and memory, motor ...
Mercedes Garcia-Gil +5 more
doaj +1 more source
A Note on Serum Nucleotidase Determinations [PDF]
Clinical Chemistry and Laboratory Medicine, 1971 Current methods for estimating 5'-nucleotidase activity in human serum are critically discussed. The requirements for specificity in the assay procedure are re-emphasised, special consideration being given to the absolute concentrations as well as the molar ratios of true and alternative substrates.
Belfield, A., GOLDBERG, D. M.
openaire +2 more sources
Adenosine—A Regulator of Human Testicular Peritubular Cells
Andrology, EarlyView.ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz +12 more
wiley +1 more source
Pyrimidine nucleotidases from human erythrocyte possess phosphotransferase activities specific for pyrimidine nucleotides [PDF]
, 1997 Two cytoplasmic forms of pyrimidine nucleotidase (PN-I and PN-II) have been purified from human erythrocytes to apparent homogeneity and partially characterized.
Ruggieri, Silverio +10 more
core +1 more source
Ectonucleotidases in Acute and Chronic Inflammation
Frontiers in Pharmacology, 2021 Ectonucleotidases are extracellular enzymes with a pivotal role in inflammation that hydrolyse extracellular purine and pyrimidine nucleotides, e.g., ATP, UTP, ADP, UDP, AMP and NAD+. Ectonucleotidases, expressed by virtually all cell types, immune cells
Anna Lisa Giuliani +2 more
doaj +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2004 The studies aiming to understand the function of purinoceptors in the central nervous system (CNS), which has been explored mostly in isolated and cultured cell systems, are now at the stage of identifying their physiological and pathophysiological ...
Fusao Kato +4 more
doaj +1 more source
Pharmaceuticals, 2022 Cytosolic nucleotidases (cNs) catalyze dephosphorylation of nucleoside 5’-monophosphates and thereby contribute to the regulation of nucleotide levels in cells.
Dorota Kubacka +8 more
doaj +1 more source
Insect Molecular Biology, EarlyView.Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto +2 more
wiley +1 more source
Neotropical IchthyologyRhamdia quelen (silver catfish) and Leporinus obtusidens (piava) were exposed to a commercial formulation Roundup(r), a glyphosate-based herbicide at concentrations of 0.2 or 0.4 mg/L for 96 h.
Vania Lucia Loro +8 more
doaj +1 more source