Results 111 to 120 of about 1,867,455 (347)
FEBS Open Bio, EarlyView.Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
NUCLEOTIDE PYROPHOSPHATASE AND TRIPHOSPHOPYRIDINE NUCLEOTIDE STRUCTURE [PDF]
Journal of Biological Chemistry, 1948 openaire +2 more sources
The nucleotides that bind [PDF]
Nature Structural & Molecular Biology, 2021 openaire +2 more sources
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences
Bioinform., 2006 Weizhong Li, A. Godzik
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
Mechanisms of Synthesis of Purine Nucleotides in Heart Muscle Extracts1 [PDF]
, 1957 David A. Goldthwait
openalex +1 more source
FEBS Open Bio, EarlyView.In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source