Results 141 to 150 of about 2,769,148 (383)

Global reprogramming of virulence and antibiotic resistance in Pseudomonas aeruginosa by a single nucleotide polymorphism in elongation factor, fusA1

, 2020
Eve A. Maunders, Rory C. Triniman, Joshua Western, Taufiq Rahman, Martin Welch   +4 more
openalex   +1 more source

DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context [PDF]

, 2016
Vera P. Pisareva, Andrey V. Pisarev
openalex   +1 more source

Single Nucleotides Polymorphisms in COX2 Gene and their Association with Signs and Symptoms of Teething – A Pilot Study [PDF]

, 2023
Alana Gonçalvez Mauta, Caio Luiz Bitencourt Reis, Vinicius Broska Teodoro, Isabela Ribeiro Madalena, Christian Kirschneck, Peter Proff, Aleysson Olímpio Paza, Flares Baratto‐Filho, Daniela Silva Barroso de Oliveira, Érika Calvano Küchler, João Armando Brancher   +10 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

The Synergistic Effect of N2 and N7 Modifications on the Inhibitory Efficacy of mRNA Cap Analogues

Pharmaceuticals
In the fight against cancer, researchers have turned their attention to the eukaryotic initiation factor eIF4E, a protein whose increased level is strongly correlated with the development and progression of various types of cancer.
Karol Kurpiejewski, Karolina Piecyk, Maciej Lukaszewicz, Karol Kamel, Kazimierz Chmurski, Sebastian Kmiecik, Marzena Jankowska-Anyszka   +6 more
doaj   +1 more source

A novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells [PDF]

, 2020
Fan Gao, Ye Cai, Lu Tang, Chunlin Wu, Huifen Cao, Dongyang Xu, Lorena Salazar‐García, Xueer Han, Fang Wang, Natalie Ricciardi, Thor Wahlestedt, Dingding Cai, Huifang Wang, Mario P. S. Chin, James A. Timmons, Claes Wahlestedt, Philipp Kapranov   +16 more
openalex   +1 more source

味噌醤油酵母Zygosaccharomyces酵母の接合遺伝子座(mating-type-like (MTL) loci)の多様性 [PDF]

, 2018
Variations of chromosomal structures and nucleotide sequences around mating-type-like (MTL) loci among Zygosaccharomyces species have been reported.
Ogata, Tomoo, オガタ, トモオ, 尾形, 智夫   +2 more
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

The Acid-soluble Nucleotides of Barley and Oat Plants. [PDF]

, 1957
Rolf Bergkvist, Gunnel Westöö, Lars Svennerholm, Arne Magnéli, Arne Magnéli, Herbert Pestmalis, Stig Åsbrink   +6 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source