Results 151 to 160 of about 2,769,148 (383)

Nucleotide polymorphism in colicin E2 gene clusters: evidence for nonneutral evolution [PDF]

, 1997
Yonggang Tan, Andrew M. Riley
openalex   +1 more source

Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences

Bioinform., 2006
Weizhong Li, A. Godzik
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles

, 2020
Anupam Singh, Manjula Pandey, Divya Nandakumar, Kevin D. Raney, Y. Whitney Yin, Smita S. Patel   +5 more
openalex   +1 more source

Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.

Molecular biology and evolution, 1993
Kazuko Tamura, M. Nei
semanticscholar   +1 more source

A two-phase approach for detecting recombination in nucleotide sequences

, 2007
Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. Delineating recombination events is important in the study of molecular evolution, as inference of such events provides a clearer picture of the ...
Beiko, Robert G., Chan, Cheong Xin, Ragan, Mark A.   +2 more
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Nucleotide sequence of the yeast alcohol dehydrogenase II gene.

, 1983
David W. Russell, Michael J. Smith, Valerie M. Williamson, E T Young   +3 more
openalex   +1 more source

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

Fly, 2012
Pablo Cingolani, A. Platts, Le Lily Wang, M. Coon, Tung Nguyen, Luan Wang, S. Land, Xiangyi Lu, D. Ruden   +8 more
semanticscholar   +1 more source