Results 11 to 20 of about 1,867,455 (347)
Biology, 2020 Machine learning algorithms can learn mechanisms of antimicrobial resistance from the data of DNA sequence without any a priori information. Interpreting a trained machine learning algorithm can be exploited for validating the model and obtaining new ...
Taha ValizadehAslani +3 more
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Animals, 2021 The positive effects of nucleotide (NU) supplementation in milk replacer have been elucidated in infants and in dairy calves; however, NU addition to whole milk has not been evaluated previously. This study aimed to assess NU supplementation in the whole
Yousef Abbaslou +5 more
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Frontiers in Cell and Developmental Biology, 2023 The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β tubulin,
Alya Hussain +3 more
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Molecular analysis of ompA gene Pasteurella multocida Indonesia local isolates [PDF]
Iraqi Journal of Veterinary Sciences, 2020 The aim of this research was to analyze ompA molecular gene of Pasteurella multocida buffalo isolate and bovine isolate from Nusa Tenggara Timur, Indonesia and Katha strain isolate from hemorrhagic septicemia vaccine. Determinant of P.
A. T. Soelih Estoepangestie +5 more
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Angewandte Chemie International Edition, 2011 DNA as an information storage system is simple and at the same time complex owing to the various different arrangements of the four natural nucleotides.[1] The DNA synthesis by DNA polymerases is intriguing, since these enzymes are able to catalyze the elongation of the primer strand by recognizing the DNA template and selecting the corresponding ...
Baccaro, Anna +2 more
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Crystallographic observation of nonenzymatic RNA primer extension
eLife, 2018 The importance of genome replication has inspired detailed crystallographic studies of enzymatic DNA/RNA polymerization. In contrast, the mechanism of nonenzymatic polymerization is less well understood, despite its critical role in the origin of life ...
Wen Zhang +3 more
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Pharmaceuticals, 2022 Von Willebrand Factor (VWF) plays a critical role in thrombus formation, stabilization, and propagation. Previous studies have demonstrated that targeted inhibition of VWF induces thrombolysis when administered in vivo in animal models of ischemic stroke.
Susan M. Shea +7 more
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Nucleotide-decorated AuNPs as probes for nucleotide-binding proteins [PDF]
Scientific Reports, 2021 AbstractGold nanoparticles (AuNPs) decorated with biologically relevant molecules have variety of applications in optical sensing of bioanalytes. Coating AuNPs with small nucleotides produces particles with high stability in water, but functionality-compatible strategies are needed to uncover the full potential of this type of conjugates.
Maciej Mazur +7 more
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Frontiers in Cellular and Infection Microbiology, 2023 Maintenance of dNTPs pools in Trypanosoma brucei is dependent on both biosynthetic and degradation pathways that together ensure correct cellular homeostasis throughout the cell cycle which is essential for the preservation of genomic stability. Both the
Pablo Antequera-Parrilla +4 more
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Targeting nucleotide metabolism: a promising approach to enhance cancer immunotherapy
Journal of Hematology & Oncology, 2022 Targeting nucleotide metabolism can not only inhibit tumor initiation and progression but also exert serious side effects. With in-depth studies of nucleotide metabolism, our understanding of nucleotide metabolism in tumors has revealed their non ...
Huai-liang Wu +5 more
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