Results 11 to 20 of about 1,684,114 (372)
Minimap2: pairwise alignment for nucleotide sequences [PDF]
Bioinform., 2017 Motivation Recent advances in sequencing technologies promise ultra-long reads of ∼100 kb in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 Mb in length.
Heng Li
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Nucleotide metabolism: a pan-cancer metabolic dependency
Nature Reviews. Cancer, 2023 Overactive nucleotide synthesis is a hallmark of cancers and inhibitors of nucleotide synthesis pathways have shown promise in some cancer types. In this Review, Mullen and Singh give an overview of the role of aberrant nucleotide synthesis in supporting
Nick Mullen, Pankaj Singh
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Angewandte Chemie International Edition, 2011 DNA as an information storage system is simple and at the same time complex owing to the various different arrangements of the four natural nucleotides.[1] The DNA synthesis by DNA polymerases is intriguing, since these enzymes are able to catalyze the elongation of the primer strand by recognizing the DNA template and selecting the corresponding ...
Baccaro, Anna +2 more
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Nucleotide-decorated AuNPs as probes for nucleotide-binding proteins [PDF]
Scientific Reports, 2021 AbstractGold nanoparticles (AuNPs) decorated with biologically relevant molecules have variety of applications in optical sensing of bioanalytes. Coating AuNPs with small nucleotides produces particles with high stability in water, but functionality-compatible strategies are needed to uncover the full potential of this type of conjugates.
Maciej Mazur +7 more
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N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling
Frontiers in Immunology, 2022 Toll-like receptors (TLRs) play critical roles in the first line of host defense against pathogens through recognition of pathogen-associated molecular patterns and initiation of the innate immune responses.
Hyun-Sup Song +10 more
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Frontiers in Environmental Science, 2022 Nucleic acid derived organic phosphorus (Po) is an important source of plant available P when degraded to inorganic phosphate (P(V)i). It is known that when nucleic acids or components are adsorbed on mineral surfaces, the enzymatic degradation is ...
Sudipta Rakshit +3 more
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On the verge of life: Distribution of nucleotide sequences in viral RNAs [PDF]
Biosemiotics 14, No. 2, 253-269 (2021), 2020 The aim of the study is to analyze viruses using parameters obtained from distributions of nucleotide sequences in the viral RNA. Seeking for the input data homogeneity, we analyze single-stranded RNA viruses only. Two approaches are used to obtain the nucleotide sequences; In the first one, chunks of equal length (four nucleotides) are considered.
arxiv +1 more source
Molecular biology and evolution, 1993 Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new mathematical method for estimating the number of transitional and transversional substitutions per site, as
Kazuko Tamura, M. Nei
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Animals, 2021 The positive effects of nucleotide (NU) supplementation in milk replacer have been elucidated in infants and in dairy calves; however, NU addition to whole milk has not been evaluated previously. This study aimed to assess NU supplementation in the whole
Yousef Abbaslou +5 more
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Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences
Bioinform., 2006 MOTIVATION In 2001 and 2002, we published two papers (Bioinformatics, 17, 282-283, Bioinformatics, 18, 77-82) describing an ultrafast protein sequence clustering program called cd-hit.
Weizhong Li, A. Godzik
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