Results 11 to 20 of about 2,769,148 (383)

Amino Acid k-mer Feature Extraction for Quantitative Antimicrobial Resistance (AMR) Prediction by Machine Learning and Model Interpretation for Biological Insights

open access: yesBiology, 2020
Machine learning algorithms can learn mechanisms of antimicrobial resistance from the data of DNA sequence without any a priori information. Interpreting a trained machine learning algorithm can be exploited for validating the model and obtaining new ...
Taha ValizadehAslani   +3 more
doaj   +1 more source

Agreement of aptamer proteomics with standard methods for measuring venous thrombosis biomarkers

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Venous thromboembolism (VTE) is a complex disease with an incidence rate of about 1 in 1000 per year. Despite the availability of validated biomarkers for VTE, unprovoked events account for 50% of first events.
Tariq Faquih   +5 more
doaj   +1 more source

Stimuli-Responsive Nucleotide–Amino Acid Hybrid Supramolecular Hydrogels

open access: yesGels, 2021
The ability to assemble chemically different gelator molecules into complex supramolecular hydrogels provides excellent opportunities to construct functional soft materials.
Matthew Mulvee   +3 more
doaj   +1 more source

Molecular analysis of ompA gene Pasteurella multocida Indonesia local isolates [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2020
The aim of this research was to analyze ompA molecular gene of Pasteurella multocida buffalo isolate and bovine isolate from Nusa Tenggara Timur, Indonesia and Katha strain isolate from hemorrhagic septicemia vaccine. Determinant of P.
A. T. Soelih Estoepangestie   +5 more
doaj   +1 more source

Nucleotide Frequencies in Human Genome and Fibonacci Numbers [PDF]

open access: yes, 2006
This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions.
A. Dress   +14 more
core   +2 more sources

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]

open access: yes, 2000
We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
Boonstra, B   +4 more
core   +2 more sources

Intracellular management of information: from DNA to proteins

open access: yestripleC: Communication, Capitalism & Critique, 2009
The living features of cells constitute an information flow from a central database, the nuclear DNA, to molecular effectors, proteins, which are synthesised in the cytoplasm.
Juan M. Lara
doaj   +1 more source

Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of Arterial Occlusion

open access: yesPharmaceuticals, 2022
Von Willebrand Factor (VWF) plays a critical role in thrombus formation, stabilization, and propagation. Previous studies have demonstrated that targeted inhibition of VWF induces thrombolysis when administered in vivo in animal models of ischemic stroke.
Susan M. Shea   +7 more
doaj   +1 more source

Gastroprotective effects of oral nucleotide administration [PDF]

open access: yes, 2006
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A   +4 more
core   +2 more sources

Genetic variability of Taenia saginata inferred from mitochondrial DNA sequences [PDF]

open access: yes, 2015
Taenia saginata is an important tapeworm, infecting humans in many parts of the world. The present study was undertaken to identify inter- and intraspecific variation of T.
Babaei, Z.   +5 more
core   +1 more source

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