Results 31 to 40 of about 1,677,228 (315)

Comparative analysis of taste compounds in shiitake mushrooms processed by hot-air drying and freeze drying

International Journal of Food Properties, 2019
Shiitake mushrooms were processed by hot-air drying (HD) and freeze-drying (FD) to investigate the taste compounds. The total free amino acids in HD samples treated at 60°C was the highest as compared to the other three dried samples.
Xiao Yang, Yuyu Zhang, Yan Kong, Jing Zhao, Ying Sun, Mingquan Huang   +5 more
doaj   +1 more source

The Interactions of Anti-HIV Pronucleotides with a Model Phospholipid Membrane

Molecules
Pronucleotides, after entering the cell, undergo chemical or enzymatic conversion into nucleotides with a free phosphate residue, and the released nucleoside 5′-monophosphate is then phosphorylated to the biologically active form, namely nucleoside 5 ...
Monika Rojewska, Joanna Romanowska, Adam Kraszewski, Michał Sobkowski, Krystyna Prochaska   +4 more
doaj   +1 more source

Profile of Nucleotides and Nucleosides in Taiwanese Human Milk

Pediatrics and Neonatology, 2011
Human milk–borne nucleotides and their related metabolic products have been reported to have important physiological roles in breast-fed infants. The purpose of this study was to measure the concentrations of free nucleotides and nucleosides in human ...
Kuo-Yu Liao, Tzee-Chung Wu, Ching-Feng Huang, Chih-Chung Lin, I-Fei Huang, Lite Wu   +5 more
doaj   +1 more source

Exploring the nucleotide molecular mechanism of compound kushen injection for lung adenocarcinoma based on network pharmacology and molecular docking

Frontiers in Oncology, 2022
Compound kushen injection is an effective traditional Chinese medicine for the treatment of lung cancer. However, its influence on the survival and prognosis of patients with lung adenocarcinoma patients was less studied; especially its pharmacological ...
Zhangpeng Ye, Zhangpeng Ye, Xin Yao, Xin Yao, Zhubei Chen, Zhubei Chen, Qin Jin, Qin Jin, Qingsheng You, Qingsheng You   +9 more
doaj   +1 more source

Nucleotide-Dependent Bioautocatalytic Timer Reaction

, 2016
We describe a biochemical timer composed of three biocatalytic reactions involving three types of adenylate nucleotides: adenosine triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP).
Ting-Ru Chen (2820472), Ching-Fong Hsu (2820475), Pawel L. Urban (120250), Henryk A. Witek (1767706), Chih-Lin Chen (2820469)   +4 more
core   +1 more source

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers [PDF]

, 2006
BackgroundThe MDM2 gene encodes a negative regulator of the p53 tumour suppressor protein. A single nucleotide polymorphism (SNP) in the MDM2 promoter (a T to G exchange at nucleotide 309) has been reported to produce accelerated tumour formation in ...
Johnson, Peter W., White Helen E, Jeremy P Blaydes, Diana M Eccles, White, Helen E., Ellen R Copson, Johnson Peter W, Eccles Diana M, Eccles, Diana M., Helen E White, Robinson, David O., David O Robinson, Peter W Johnson, Blaydes, Jeremy P., Copson, Ellen R., Robinson David O, Copson Ellen R, Blaydes Jeremy P   +17 more
core   +2 more sources

SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites

Molecular Therapy: Nucleic Acids
Assisted reproductive technology (ART) is used widely and efficiently to treat infertility. During the ART procedure, one of the main factors affecting the success rate is abnormal development of preimplantation embryos. The establishment and maintenance
Mingze Shi, Yingxue Huai, Tiantian Deng, Chuanxin Zhang, Jinzhu Song, Jiawei Wang, Yiwen Zhang, Zi-Jiang Chen, Han Zhao, Keliang Wu, Boyang Liu   +10 more
doaj   +1 more source

Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides

Pharmaceuticals, 2018
Vitamin E phosphate (VEP) nucleoside prodrugs are designed to bypass two mechanisms of tumor resistance to therapeutic nucleosides: nucleoside transport and kinase downregulation.
Richard Daifuku, Michael Koratich, Murray Stackhouse   +2 more
doaj   +1 more source

Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken

International Journal of Food Properties, 2020
Taste is one of the main chicken soup characteristic quality factors as it affects palatability as well as consumer acceptability. Metabolomics coupled with sensory analysis method were applied to explore the differences of taste-chemical compositions in
Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu   +7 more
doaj   +1 more source

Morpholino–RNA duplex exhibits robust, sustained, and safe steric-block antisense activity by intracerebroventricular and intrathecal injection

Nature Communications
Intrathecal injection of steric-block antisense oligonucleotides (ASOs) provides therapeutic opportunities for targeting the central nervous system (CNS).
Mitsugu Yanagidaira, Tetsuya Nagata, Juri Hasegawa, Takashi Ishii, Satoe Ebihara, Makiko Nawa, Takanori Yokota   +6 more
doaj   +1 more source