Results 321 to 330 of about 2,548,202 (389)

The Isoforms of Ral Guanine Nucleotide Dissociation Stimulator (RalGDS) in LLC-PK1 Cells. [PDF]

Curr Issues Mol Biol
Song J, Li N, Dong X, Xie J, Lai H, Zhu H, He K, Wen L, Suolang S, Xiao Q.   +9 more
europepmc   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Innovative data augmentation strategy for deep learning on biological datasets with limited gene representations focused on chloroplast genomes. [PDF]

Sci Rep
Abbasi-Vineh MA, Rouzbahani S, Kavousi K, Emadpour M.   +3 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Highly Conserved Genetic Factors Regulating <i>bla</i>_NDM Gene Expression. [PDF]

J Microbiol Biotechnol
Xu J, Zhu J, Mei C, Liu X, Gong Z, Huang J, Chai H.   +6 more
europepmc   +1 more source

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

Molecular characteristics of human adenovirus isolated from the 2024 influenza-like illness outbreaks in Suzhou City, China. [PDF]

Virol J
Zang J, Xing Y, Zhang H, Wu Y, Ya X, Shen Q, Dong Z.   +6 more
europepmc   +1 more source

Tomato yellow leaf curl Reunion virus: a novel tomato-infecting monopartite begomovirus from Reunion Island. [PDF]

Arch Virol
Leclair P, Hoareau M, Parvedy E, Quirin E, Clain C, Roux E, Minatchy J, Teycheney PY, Lefeuvre P, Lett JM.   +9 more
europepmc   +1 more source

Whole-genome sequencing of 1,060 Brettanomyces bruxellensis isolates reveals significant phenotypic impact of acquired subgenomes in allopolyploids. [PDF]

Nat Commun
Loegler V, Runge JN, Eberlein C, Peltier É, Harrouard J, Miot-Sertier C, Albertin W, Friedrich A, Schacherer J.   +8 more
europepmc   +1 more source