Results 331 to 340 of about 1,684,114 (372)

Nucleotide Excision Repair

Definitions, 2006
European Bioinformatics Institute, New York University Langone Medical Center, Ontario Institute for Cancer Research, Oregon Health and Science University.
W. Mcgregor
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Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome.

Science, 1998
Single-nucleotide polymorphisms (SNPs) are the most frequent type of variation in the human genome, and they provide powerful tools for a variety of medical genetic studies.
David G. Wang, Jian-Bing Fan, C. Siao, Anthony Berno, Peter Young, R. Sapolsky, G. Ghandour, Nancy Perkins, E. Winchester, Jessica B. Spencer, L. Kruglyak, Lincoln Stein, L. Hsie, T. Topaloglou, E. Hubbell, Elizabeth Robinson, Mike Mittmann, M. S. Morris, Naiping Shen, D. Kilburn, J. Rioux, C. Nusbaum, S. Rozen, T. Hudson, R. Lipshutz, M. Chee, E. Lander   +26 more
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Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

Pharmacological Reviews, 2006
Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that regulate the cellular levels of the second messengers, cAMP and cGMP, by controlling their rates of degradation.
Andrew T. Bender, J. Beavo
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Fluorinated Nucleosides, Nucleotides and Sugar Nucleotides

Future Medicinal Chemistry, 2023
Jonathan P Dolan, Caecilie MM Benckendorff, Robert A Field, Gavin J Miller   +3 more
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Reduction of cytidine nucleotides to deoxycytidine nucleotides by mammalian enzymes

Biochimica et Biophysica Acta, 1962
Abstract 1. 1. Conditions for the reduction in vitro of cytidine nucleotides to deoxycytidine nucleotides by an extract of the Novikoff ascites rat tumor are described. ATP was required; TPN, Mg 2+ and Fe 3+ stimulated the reaction. The effects of other metal ions and of a number of organic compounds on the reaction are described. 2.
Robert B. Hurlbert, E. Colleen Moore
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Nucleotide und Nucleinsäuren

2002
Nucleotide wurden erstmals als Bausteine der Nucleinsauren gefunden. Sie sind in charakteristischer Weise aufgebaut und haben inzwischen einer ganzen Substanzklasse gleichermasen aufgebauter Verbindungen ihren Namen gegeben.
Uli Kazmaier, Hans Peter Latscha, Helmut Alfons Klein   +2 more
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Nucleotides as nucleophiles: Reactions of nucleotides with phosphoimidazolide activated guanosine

Origins of life and evolution of the biosphere, 1992
An earlier study of the reaction of phosphoimidazolide activated nucleosides (ImpN) in aqueous phosphate buffers indicated two modes of reaction of the phosphate monoanion and dianion. The first mode is catalysis of the hydrolysis of the P-N bond in ImpN's which leads to imidazole and nucleoside 5'-monophosphate.
Anastassia Kanavarioti, Morgan T. Rosenbach, T. B. Hurley   +2 more
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The Guanine Nucleotide-Binding Switch in Three Dimensions

Science, 2001
Guanine nucleotide–binding proteins regulate a variety of processes, including sensual perception, protein synthesis, various transport processes, and cell growth and differentiation.
I. Vetter, A. Wittinghofer
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A new adenine nucleotide

Biochimica et Biophysica Acta, 1953
Abstract A new nucleotide has been shown to be present in commercial samples of adenosine-5′-triphosphate (ATP). The analytical data suggest the structure adenosine-5′-tetraphosphate.
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Nucleotides and nucleotide derivatives as signal molecules in plants

Journal of Experimental Botany
Abstract In reaction to a stimulus, signaling molecules are made, generate a response, and are then degraded. Nucleotides are classically associated with central metabolism and nucleic acid biosynthesis, but there are a number of nucleotides and nucleotide derivatives in plants to which this simple definition of a signaling molecule ...
Claus-Peter Witte, Marco Herde
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