Results 31 to 40 of about 2,769,148 (383)
EFFECTS OF DIETARY NUCLEOTIDES SUPPLEMENTATION ON THE PERFOR-MANCE OF BROILER CHICKS
This study examined the effects of nucleotide supplementation on broiler chick growth performance, immunological response, carcass traits, meat quality, serum biochemical parameters, total antioxidant capacity, intestinal morphology, mortality rate, and
Isayed I. Hassanein +2 more
doaj +1 more source
Inhibition of Subsets of G Protein-coupled Receptors by Empty Mutants of G Protein α Subunits in Go, G11, and G16 [PDF]
We previously reported that the xanthine nucleotide binding Goα mutant, GoαX, inhibited the activation of Gi-coupled receptors. We constructed similar mutations in G11α and G16α and characterized their nucleotide binding and receptor interaction.
Gu, Lingjie, Simon, Melvin I., Yu, Bo
core +1 more source
ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. [PDF]
Leukemia cells rely on two nucleotide biosynthetic pathways, de novo and salvage, to produce dNTPs for DNA replication. Here, using metabolomic, proteomic, and phosphoproteomic approaches, we show that inhibition of the replication stress sensing kinase ...
Abt, Evan R +20 more
core +2 more sources
Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif [PDF]
Heterotrimeric G proteins are quintessential signalling switches activated by nucleotide exchange on Gα. Although activation is predominantly carried out by G-protein-coupled receptors (GPCRs), non-receptor guanine-nucleotide exchange factors (GEFs) have
Baillie, George S. +14 more
core +1 more source
Shiitake mushrooms were processed by hot-air drying (HD) and freeze-drying (FD) to investigate the taste compounds. The total free amino acids in HD samples treated at 60°C was the highest as compared to the other three dried samples.
Xiao Yang +5 more
doaj +1 more source
RNA interference is mediated by 21- and 22-nucleotide RNAs.
Double-stranded RNA (dsRNA) induces sequence-specific posttranscriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we demonstrate that 21- and 22-nt RNA fragments are the sequence-
Sayda M. Elbashir +2 more
semanticscholar +1 more source
The Interactions of Anti-HIV Pronucleotides with a Model Phospholipid Membrane
Pronucleotides, after entering the cell, undergo chemical or enzymatic conversion into nucleotides with a free phosphate residue, and the released nucleoside 5′-monophosphate is then phosphorylated to the biologically active form, namely nucleoside 5 ...
Monika Rojewska +4 more
doaj +1 more source
Profile of Nucleotides and Nucleosides in Taiwanese Human Milk
Human milk–borne nucleotides and their related metabolic products have been reported to have important physiological roles in breast-fed infants. The purpose of this study was to measure the concentrations of free nucleotides and nucleosides in human ...
Kuo-Yu Liao +5 more
doaj +1 more source
Compound kushen injection is an effective traditional Chinese medicine for the treatment of lung cancer. However, its influence on the survival and prognosis of patients with lung adenocarcinoma patients was less studied; especially its pharmacological ...
Zhangpeng Ye +9 more
doaj +1 more source
Food-chain competition influences gene's size
We have analysed an effect of the Bak-Sneppen predator-prey food-chain self-organization on nucleotide content of evolving species. In our model, genomes of the species under consideration have been represented by their nucleotide genomic fraction and we
Bak +16 more
core +1 more source

