Results 201 to 210 of about 127,063 (412)

Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21 [PDF]

, 1995
Zhen‐Qiang Pan, Joyce T. Reardon, Lei Li, Hernan Flores‐Rozas, Randy J. Legerski, Aziz Sancar, Jerard Hurwitz   +6 more
openalex   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Human nucleotide excision repairin vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract

, 1989
Sibghat-Ullah, Intisar Husain, Wendi Carlton, A Sancar   +3 more
openalex   +2 more sources

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases

Advanced Science, EarlyView.
This study develops RLS‐2, a high‐affinity aptamer that specifically targets injured podocytes, making it a promising candidate for targeted drug delivery. In vitro, RLS‐2 shows stability, specificity, efficient siRNA delivery via AsiCs, and uptake by podocytes.
Chao Zhou, Zhaofeng Luo, Zheng Zhang, Qing Ye, Dongjie Wang, Hanyan Meng, Jiayu Zhang, Shifan Zhu, Lidan Hu, Jianhua Mao   +9 more
wiley   +1 more source

Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma. [PDF]

Sci Rep, 2023
Prosz A, Duan H, Tisza V, Sahgal P, Topka S, Klus GT, Börcsök J, Sztupinszki Z, Hanlon T, Diossy M, Vizkeleti L, Stormoen DR, Csabai I, Pappot H, Vijai J, Offit K, Ried T, Sethi N, Mouw KW, Spisak S, Pathania S, Szallasi Z.   +21 more
europepmc   +1 more source

DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.

, 1993
Daniel Svoboda, John‐Stephen Taylor, John E. Hearst, A. Sancar   +3 more
openalex   +1 more source

The C-terminal Domain of p21 Inhibits Nucleotide Excision Repair In Vitro and In Vivo [PDF]

, 1999
Marcus P. Cooper, Adayabalam S. Balajee, Vilhelm A. Bohr   +2 more
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Defining the Roles of Nucleotide Excision Repair and Recombination in the Repair of DNA Interstrand Cross-Links in Mammalian Cells [PDF]

, 2000
Inusha U. De Silva, Peter J. McHugh, Peter H. Clingen, John A. Hartley   +3 more
openalex   +2 more sources

Specificity of the yeast rev3 delta antimutator and REV3 dependency of the mutator resulting from a defect (rad1 delta) in nucleotide excision repair.

, 1994
Hazeline Roche, R D Gietz, Bernard A. Kunz   +2 more
openalex   +2 more sources