IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu+10 more
wiley +1 more source
Distinct genomic features and mutational signatures of nucleotide excision repair and mismatch repair in thymoma. [PDF]
Cheng PL+6 more
europepmc +1 more source
TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. [PDF]
Bariani MV+9 more
europepmc +1 more source
PostExcision Events in Human Nucleotide Excision Repair
M. Kemp, Jinchuan Hu
semanticscholar +1 more source
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang+11 more
wiley +1 more source
Regulation of nucleotide excision repair by wild-type HRAS signaling in head and neck cancer. [PDF]
Hoxhallari L+13 more
europepmc +1 more source
Single-molecule fluorescence microscopy on nucleotide excision repair complexes using GFP fusion proteins [PDF]
Ine Segers‐Nolten+6 more
openalex +1 more source
Nucleotide excision repair is impaired by binding of transcription factors to DNA
R. Sabarinathan+4 more
semanticscholar +1 more source
DECENT is a deep learning method that enhances noninvasive preimplantation genetic testing by accurately reconstructing embryonic copy number variations (CNVs) from cell‐free DNA in spent embryo culture media. By mitigating maternal contamination, DECENT improves diagnostic accuracy, even with high contamination levels, offering a reliable, noninvasive
Zhenyi Zhang+3 more
wiley +1 more source
XPC-RAD23B enhances UV-DDB binding to DNA to facilitate lesion search in nucleotide excision repair. [PDF]
An S+10 more
europepmc +1 more source