Results 211 to 220 of about 98,783 (332)

A pooled analysis of host factors that affect nucleotide excision repair in humans. [PDF]

Mutagenesis
Zheng C, Shaposhnikov S, Collins A, Brunborg G, Azqueta A, Langie SAS, Dusinska M, Slyskova J, Vodicka P, van Schooten FJ, Bonassi S, Milic M, Orlow I, Godschalk R.   +13 more
europepmc   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Involvement of Nucleotide Excision Repair and Rec-Dependent Pathway Genes for UV Radiation Resistance in Deinococcus irradiatisoli 17bor-2. [PDF]

Genes (Basel), 2023
Subramani G, Srinivasan S.
europepmc   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

The aflatoxin B₁-induced formamidopyrimidine adduct is repaired by transcription-coupled nucleotide excision repair in human cells. [PDF]

NAR Cancer
Laverty DJ, Tomar R, Erlich S, Stone MP, Nagel ZD.   +4 more
europepmc   +1 more source

The Xeroderma Pigmentosum Group E Gene Product DDB2 Activates Nucleotide Excision Repair by Regulating the Level of p21^Waf1/Cip1

, 2007
Tanya Stoyanova, Taewon Yoon, Dragana Kopanja, Margalit B. Mokyr, Pradip Raychaudhuri   +4 more
openalex   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Cancer-associated fibroblast derived CXCL14 drives cisplatin chemoresistance by enhancing nucleotide excision repair in bladder cancer. [PDF]

J Exp Clin Cancer Res
Li T, Zhu K, Tong H, Sun Y, Zhu J, Qin Z, Chen J, Wu L, Zhang X, Wang A, Gou X, Yin H, He W.   +12 more
europepmc   +1 more source

Decreased nucleotide excision repair in steatotic livers associates with myeloperoxidase-immunoreactivity

, 2011
Marten A. Schults, Peter W. Nagle, Sander S. Rensen, Roger Godschalk, Armelle Munnia, Marco Peluso, Sandra M.H. Claessen, Jan Greve, Ann Driessen, Froukje J. Verdam, Wim A. Buurman, Frederik‐Jan van Schooten, Roland K. Chiu   +12 more
openalex   +2 more sources

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source