Nucleotide excision repair removes thymidine analog 5-ethynyl-2'-deoxyuridine from the mammalian genome. [PDF]
Wang L+7 more
europepmc +1 more source
Cerebro-Oculo-Facio-Skeletal Syndrome with a Nucleotide Excision–Repair Defect and a Mutated XPD Gene, with Prenatal Diagnosis in a Triplet Pregnancy [PDF]
John M. Graham+8 more
openalex +1 more source
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang+6 more
wiley +1 more source
Evidence for intrinsic DNA dynamics and deformability in damage sensing by the Rad4/XPC nucleotide excision repair complex. [PDF]
Baral S+5 more
europepmc +1 more source
A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair. [PDF]
van den Heuvel D+16 more
europepmc +1 more source
The 19S complex of the proteasome regulates nucleotide excision repair in yeast [PDF]
Thomas G. Gillette+5 more
openalex +1 more source
Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin+9 more
wiley +1 more source
Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair. [PDF]
Fu I, Mu H, Geacintov NE, Broyde S.
europepmc +1 more source
The p53-regulated Cyclin-dependent Kinase Inhibitor, p21 (cip1, waf1, sdi1), Is Not Required for Global Genomic and Transcription-coupled Nucleotide Excision Repair of UV-induced DNA Photoproducts [PDF]
Shanthi Adimoolam+2 more
openalex +1 more source
Oxidative Damage to RPA Limits the Nucleotide Excision Repair Capacity of Human Cells.
M. Guven+4 more
semanticscholar +1 more source