Results 231 to 240 of about 98,783 (332)

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

open access: yesAdvanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang   +22 more
wiley   +1 more source

Regulation of nucleotide excision repair by wild-type HRAS signaling in head and neck cancer. [PDF]

open access: yesCancer Gene Ther
Hoxhallari L   +13 more
europepmc   +1 more source

Mechanism of action of nucleotide excision repair machinery. [PDF]

open access: yesBiochem Soc Trans, 2022
D'Souza A, Blee AM, Chazin WJ.
europepmc   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

open access: yesAdvanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme   +12 more
wiley   +1 more source

Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair. [PDF]

open access: yesNat Commun
Genta M   +10 more
europepmc   +1 more source

Nucleotide excision repair deficiency in melanoma in response to UVA

open access: gold, 2015
Heather C. Murray   +3 more
openalex   +1 more source

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