Results 231 to 240 of about 262,017 (266)

Single Nucleotide Polymorphism Mapping Using Genome-Wide Unique Sequences

Genome Research, 2002
As more and more genomic DNAs are sequenced to characterize human genetic variations, the demand for a very fast and accurate method to genomically position these DNA sequences is high. We have developed a new mapping method that does not require sequence alignment. In this method, we first identified DNA fragments of 15 bp in length that are unique in
Leslie Y Y, Chen, Szu-Hsien, Lu, Edward S C, Shih, Ming-Jing, Hwang   +3 more
openaire   +2 more sources

Mapping HLA for single nucleotide polymorphisms.

Reviews in immunogenetics, 2001
Knowledge of DNA sequence variation may help us understand how genetic variability gives rise to functional variability and, in so doing, revolutionize the development of strategies to combat and prevent disease. Single nucleotide polymorphisms (SNPs) are stable, inherited, biallelic, single base pair differences which are present in the human genome ...
D E, Geraghty, Q, Vu, L, Williams, M, Janer, C, Gassner, C, Russell, A, Ishitani, C, Jasoni   +7 more
openaire   +1 more source

Mapping genetic alterations in tumors with single nucleotide polymorphisms

Current Opinion in Oncology, 2003
Single nucleotide polymorphisms are the most abundant genetic markers in the human genome whose analyses can be easily conducted on a large scale. Most established methods for high-throughput single nucleotide polymorphism analyses are qualitative and are not suitable for genetic analysis of archived tumor specimens, which have compromised tissue ...
openaire   +2 more sources

LINKAGE DISEQUILIBRIUM MAPPING USING SINGLE NUCLEOTIDE POLYMORPHISMS -WHICH POPULATION?

Biocomputing 2000, 1999
There is considerable interest in the potential of single nucleotide polymorphisms (SNPs) for mapping complex traits which are determined by genes of small individual effect (oligogenes). It is thought likely that many oligogenes are themselves common polymorphisms, perhaps biallelic, for which there is effectively neutral selection reflected in late ...
openaire   +2 more sources

Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution

Science, 2005
Sites of transcription of polyadenylated and nonpolyadenylated RNAs for 10 human chromosomes were mapped at 5–base pair resolution in eight cell lines. Unannotated, nonpolyadenylated transcripts comprise the major proportion of the transcriptional output of the human genome.
Jill, Cheng, Philipp, Kapranov, Jorg, Drenkow, Sujit, Dike, Shane, Brubaker, Sandeep, Patel, Jeffrey, Long, David, Stern, Hari, Tammana, Gregg, Helt, Victor, Sementchenko, Antonio, Piccolboni, Stefan, Bekiranov, Dione K, Bailey, Madhavan, Ganesh, Srinka, Ghosh, Ian, Bell, Daniela S, Gerhard, Thomas R, Gingeras   +18 more
openaire   +2 more sources

[Bacterial genomes: nucleoid, chromosome, nucleotide map].

Mikrobiologiia, 1998
The structure of the genome of a bacterial cell was considered by invoking data derived by various methods, from light microscopy to sequencing of chromosomal DNA.
openaire   +1 more source

Single Nucleotide Mapping of RNA 5′ and 3′ Ends

2014
Nuclease protection assay is a sensitive method for detection, quantitation, and mapping of a specific RNA in an extremely heterogeneous mixture of RNAs, such as total cellular RNA. The assay is based on a small volume solution hybridization of a single-stranded synthetic antisense and labeled RNA probe to a RNA sample.
openaire   +2 more sources

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Nature, 2022
Vassily Trubetskoy, Antonio F Pardiñas, Georgia Panagiotaropoulou   +2 more
exaly  

A mapping procedure for nucleotides and oligonucleotides

Biochemical and Biophysical Research Communications, 1960
G W, RUSHIZKY, C A, KNIGHT
openaire   +2 more sources

Mapping the genomic diaspora of gastric cancer

Nature Reviews Cancer, 2021
Khay-Guan Yeoh, Patrick Tan
exaly