Results 251 to 260 of about 280,333 (306)

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Whole-genome sequencing with AVITI and NovaSeq X Plus reveals comparable performance with contextual biases. [PDF]

NAR Genom Bioinform
Höjer P, Alneberg J, Lundin P, Martin T, Hauenstein J, Fällmar H, Lindell M, Natanaelsson C, Häggqvist S, Ameur A, Nordlund J, Månsson Welinder R.   +11 more
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Near-complete genome sequences of equine herpesvirus (EHV) 1, EHV-3, and EHV-4 from the USA using a hybrid assembly approach. [PDF]

Microbiol Resour Announc
Uprety T, Goehring LS, Rozhbayani A, Meyer A, Todd SM, Abdelrazek S, Lahmers K, Erol E.   +7 more
europepmc   +1 more source

Molecular polymorphisms that underlie trait variation in crops: Lessons learned from soybean. [PDF]

Plant Genome
Espina MJC, Lorenz AJ, Stupar RM.
europepmc   +1 more source

A comparative analysis dataset for improving genuine SNP identification in ancient maize aDNA. [PDF]

Data Brief
Chen H, Madzima TF.
europepmc   +1 more source

Progress and challenges in profiling protein-RNA and protein-associated RNA-RNA interactions. [PDF]

RNA
Song Z, Van Nostrand EL.
europepmc   +1 more source

Bayesian fine-mapping pinpoints candidate genes and pleiotropic loci of production traits from a chicken backcrossing scheme. [PDF]

BMC Genomics
Sun CM, Geibel J, Simianer H, Andersson B, Cavero D, Preisinger R, Weigend S, Reimer C.   +7 more
europepmc   +1 more source