Results 271 to 280 of about 280,333 (306)

Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels

ACS Chemical Biology, 2014
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play a central role in the regulation of cardiac and neuronal firing rate, and these channels can be dually activated by membrane hyperpolarization and by binding of cyclic nucleotides. cAMP has been shown to directly bind HCN channels and modulate their activity.
Moller, Stefan, Alfieri, Andrea, Bertinetti, Daniela, Aquila, Marco, Schwede, Frank, Lolicato, Marco, Rehmann, Holger, Moroni, Anna, Herberg, Friedrich W.   +8 more
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Patterns of nucleotide diversity and association mapping

2011
International ...
SC GonzalezMartinez, S Dillon, PH GarnierGéré, KV Krutovsky, R Alia, C Burgarella, AJ Eckert, MR GarciaGil, D Grivet, MHeuertz, JP JaramilloCorrea, M Lascoux, DB Neale, O Savolainem, Y Tsumura, GG Vendramin   +15 more
  +7 more sources

Online Nucleotide Mapping of mRNAs

Analytical Chemistry
Messenger RNA (mRNA) can be sequenced via indirect approaches such as Sanger sequencing and next generation sequencing (NGS), or direct approaches like bottom-up mass spectrometry (MS). Direct sequencing allows the confirmation of RNA modifications.
Alexandre Goyon, Brandon Scott, Peter Yehl, Kelly Zhang   +3 more
openaire   +2 more sources

Single Nucleotide Polymorphism Mapping Array Assay

2007
Single nucleotide polymorphisms (SNPs) are the most frequent form of DNA variation present in the human genome, and millions of SNPs have been identified http://www.ncbi.nlm.nih.gov/SNP/). Because of their abundance, even spacing, and stability across the genome, SNPs have significant advantages over other genetic markers (such as restriction fragment ...
Xiaofeng, Zhou, David T W, Wong
openaire   +2 more sources

Nucleotide Excision Repair Map of Drosophila at Single Nucleotide Resolution

2022
Drosophila Melanogaster is an extensively used model system in the scientific community. It has been traditionally used to study ionizing radiation and chemical induced mutagenesis, double strand break repair and recombination. Despite these extensive work in these research areas, there are only limited number of studies on nucleotide excision repair ...
openaire   +1 more source

Development of an integrated database for genome mapping and nucleotide sequences

Proceedings of the Twenty-Seventh Hawaii International Conference on System Sciences HICSS-94, 1994
An integrated database system for genome mapping and DNA sequence data was developed. The system seamlessly manages two different types of data each of which has a unique complex structure. A graphical user interface (GUI) enables easy retrieval of information obtained from genome mapping and DNA sequence data. The map data are imported from the Genome
Takahiko Suzuki, Toshihisa Takagi, Satoru Kuhara, Minoru Kanehisa   +3 more
openaire   +1 more source

Nucleotide sequence-directed mapping of the nucleosomes of SV40 chromatin

Cell Biophysics, 1984
In our previous work we have shown by comparison of experimental and computational data that the positions of the histone octamers bound to the DNA molecule appear to be completely sequence-dependent. This provides a convenient and quick method for locating the nucleosomes along the DNA molecule, as soon as the nucleotide sequence is known.
G, Mengeritsky, E N, Trifonov
openaire   +2 more sources

Single nucleotide polymorphisms and fine mapping QTL in chickens

HEREDITAS, 2007
As an important economically animal and a model animal, a great of progress of SNP diversity and QTL mapping in chickens have been made in recent years. The present paper not only summarized these achievements but also commanded an extensive view about the fine mapping of QTL by the use of SNP marker.
You-Sheng, Rao, Xi-Quan, Zhang
openaire   +2 more sources

Development of a single nucleotide polymorphism map of porcine chromosome 2

Animal Genetics, 2003
SummarySingle nucleotide polymorphism markers are developed on SSC2, predominantly on the p‐arm. Several studies reported a quantitative trait loci (QTL) for backfat thickness in this region. Single nucleotide polymorphisms were identified by comparative re‐sequencing of polymerase chain reaction (PCR) products from a panel of eight individuals.
Jungerius, B.J., Rattink, A.P., Crooijmans, R.P.M.A., van der Poel, J.J., van Oost, B.A., te Pas, M.F.W., Groenen, M.A.M.   +6 more
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Mapping HLA for single nucleotide polymorphisms.

Reviews in immunogenetics, 2001
Knowledge of DNA sequence variation may help us understand how genetic variability gives rise to functional variability and, in so doing, revolutionize the development of strategies to combat and prevent disease. Single nucleotide polymorphisms (SNPs) are stable, inherited, biallelic, single base pair differences which are present in the human genome ...
D E, Geraghty, Q, Vu, L, Williams, M, Janer, C, Gassner, C, Russell, A, Ishitani, C, Jasoni   +7 more
openaire   +1 more source