Results 171 to 180 of about 14,893 (257)

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Natural Variation of <i>StNADC</i> Regulates Plant Senescence in Tetraploid Potatoes (<i>Solanum tuberosum</i> L.). [PDF]

Int J Mol Sci
Zhang J, Xu J, Bian C, Duan S, Hu J, Qin J, Wu H, He M, Jian Y, Duan Y, Liu J, Wang W, Li G, Jin L.   +13 more
europepmc   +1 more source

Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings

Pediatric Discovery, EarlyView.
Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong, Daniel A. Hu, Lily Zhang, Rachel Qi, Cindy Xu, Ou Mei, Guowei Shen, Wulin You, Changqi Luo, Tong‐Chuan He, Russell R. Reid, Lewis S. Shi, Michael J. Lee, Yi Zhu   +13 more
wiley   +1 more source

Targeting metabolic reprogramming in glioblastoma as a new strategy to overcome therapy resistance. [PDF]

Front Cell Dev Biol
D'Aprile S, Denaro S, Gervasi A, Vicario N, Parenti R.   +4 more
europepmc   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source

Applicability Assessment of Technologies for Predictive and Prescriptive Analytics of Nephrology Big Data

PROTEOMICS, EarlyView.
ABSTRACT The integration of big data into nephrology research will open new avenues for analyzing and understanding complex biological datasets, driving advances in personalized management of kidney diseases. This paper describes the multifaceted challenges and opportunities by incorporating big data in nephrology, emphasizing the importance of data ...
Riste Stojanov, Milos Jovanovik, Sasho Gramatikov, Igor Mishkovski, Eftim Zdravevski, Darko Sasanski, Zorica Karapancheva, Goce Spasovski, Ivona Vasileska, Tome Eftimov, Wu Zhuojun, Joachim Jankowski, Dimitar Trajanov   +12 more
wiley   +1 more source

Vulnerable Nucleotide Pools and Genomic Instability in Yeast Strains with Deletion of the <i>ADE12</i> Gene Encoding for Adenylosuccinate Synthetase. [PDF]

Int J Mol Sci
Tarakhovskaya ER, Andreychuk YV, Bilova TE, Wiesner C, Pavlov YI, Stepchenkova EI.   +5 more
europepmc   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Phosphorylation Changes SARS‐CoV‐2 Nucleocapsid Protein's Structural Dynamics and Its Interaction With RNA

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The SARS‐CoV‐2 nucleocapsid protein, or N‐protein, is a structural protein that plays an important role in the SARS‐CoV‐2 life cycle. The N‐protein takes part in the regulation of viral RNA replication and drives highly specific packaging of full‐length genomic RNA prior to virion formation.
Stefan Loonen, Lina van Steenis, Marianne Bauer, Nikolina Šoštarić   +3 more
wiley   +1 more source

Purine but Not Pyrimidine De Novo Nucleotide Biosynthesis Inhibitors Strongly Enhance the Antiviral Effect of Corresponding Nucleobases Against Dengue Virus. [PDF]

Molecules
Bonnac LF, Dreis CD, Rai M, Geraghty RJ.
europepmc   +1 more source