Results 181 to 190 of about 17,571 (268)

Landscape of targets within nucleoside metabolism for the modification of immune responses. [PDF]

Front Oncol
Dunderdale EM, Abt ER.
europepmc   +1 more source

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

Single bolus injection of nicotinamide mono nucleotide increases systemic insulin sensitivity in association with activation of NAD salvage pathway in the liver and adipose tissue in mice

Shunsuke Hiroshige, Yasuko Kajimura, Yuko Nagao, Akihiko Taguchi, Ryoko Hatanaka, Chika Yodokawa, Yuka Fujioka, Masaru Akiyama, Yukio Tanizawa, Yasuharu Ohta   +9 more
openalex   +2 more sources

Evolutionary taxonomy and conservation status of environmentally sensitive and endangered musk deer (Moschus spp.): An updated review

Conservation Science and Practice, EarlyView.
This study reviews the historical taxonomic classification and evolutionary background of musk deer, clarifying long‐standing confusion in their identification. It highlights the current global distribution and conservation status of these species, emphasizing the threat posed by poaching and habitat destruction. The work aims to raise public awareness
Zhirong Zhang, Yun Su, Wenbin Yan, Zongzhi Li, Tianhua Hu, Jiwu Zhang, Liwei Teng, Zhensheng Liu   +7 more
wiley   +1 more source

A sulfur-containing nucleoside antibiotic from <i>Photorhabdus</i>. [PDF]

mBio
Son S, Shahsavari N, Privalsky T, Hawkins BA, Lee M-H, Pitt N, Iinishi A, Taher R, Gupta N, Shankar CS, Patel J, Lewis K.   +11 more
europepmc   +1 more source

A novel kirkovirus may be associated with equine gastrointestinal disease

Equine Veterinary Journal, EarlyView.
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood, Ava Clark, Ben Hause, Breanna Sheahan   +3 more
wiley   +1 more source

Breast milk-saliva interactions in shaping early mucosal immunity. [PDF]

Front Immunol
Song SB, Kim JY.
europepmc   +1 more source

Pyrimidine nucleotide biosynthesis : an evaluation of the role of the de novo and salvage pathways in rat bone marrow and spleen /

, 1975
Donald E. Troike
openalex   +1 more source

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

The FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott, Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor, Friedrich W. Herberg   +6 more
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source