Results 201 to 210 of about 30,194 (292)

Purine Metabolism and Dystonia: Perspectives of a Long-Promised Relationship. [PDF]

Ann Neurol
Sorrentino U, O'Neill AG, Kollman JM, Jinnah HA, Zech M.   +4 more
europepmc   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Exploring Aspartate Transcarbamoylase: A Promising Broad-Spectrum Target for Drug Development. [PDF]

Chembiochem
Chen S, Mondile Q, Du X, Wang C, Mukim M, Wrenger C, Dömling ASS, Tastan Bishop Ö, Groves MR.   +8 more
europepmc   +1 more source

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

Interdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu, Zhendong Huang, Xiner Tan, Wei Du, Ziyang Wang, Xinru Zhou, Hao Pan, Lili Chen, Yiyuan Kang, Longquan Shao   +9 more
wiley   +1 more source

Enhancing cellulase biosynthesis of <i>Bacillus subtilis</i> Z2 by regulating intracellular NADH level. [PDF]

iScience
Liu S, Li Y, Quan L, Liu HX, Luo Y, Wang YZ.   +5 more
europepmc   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Histology-resolved proteomics reveals distinct tumor and stromal profiles in low- and high-grade prostate cancer. [PDF]

Clin Proteomics
Hunt AL, Barakat W, Makohon-Moore SC, Hood BL, Conrads KA, Wilson KN, Abulez T, Ogata J, Pienta KJ, Lotan TL, Mani H, Trump DL, Bateman NW, Conrads TP.   +13 more
europepmc   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

CRISPR/Cas9 editing of two adenine phosphoribosyl transferase coding genes reveals the functional specialization of adenine salvage proteins in common bean. [PDF]

J Exp Bot
López CM, Alseekh S, Martínez Rivas FJ, Fernie AR, Prieto P, Alamillo JM.   +5 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source