Results 211 to 220 of about 17,571 (268)

The potato cyst nematode Globodera pallida overcomes major potato resistance through selection on standing variation at a single locus

New Phytologist, EarlyView.
Summary Globodera pallida poses a major threat to potato production, with management strategies primarily relying on genetic resistance. However, increasing virulence in field populations across Western Europe raises major concerns for G. pallida control.
Arno S. Schaveling, Dennie M. te Molder, Paul Heeres, Joris J. M. van Steenbrugge, Stefan J. S. van de Ruitenbeek, Casper C. van Schaik, Sven van den Elsen, Geert Smant, Mark G. Sterken   +8 more
wiley   +1 more source

Targeting NAD⁺ Salvage Suppresses PBMC Inflammation to Improve Cognitive Function in Vascular Cognitive Impairment. [PDF]

Stroke
Li Z, Zhang HY, Feng R, Qi WX, Wang YT, Li Q, Zhang K.   +6 more
europepmc   +1 more source

Decoding plant defense signaling using the defenseless mutant

New Phytologist, EarlyView.
Summary Can plants live without defenses? Mutant analysis in Arabidopsis thaliana has identified numerous regulators of biotic, abiotic, and hormone‐based defenses, but the redundancy among separate defense pathways remains unexplored. We constructed an Arabidopsis mutant, defenseless, lacking six canonical defense pathways using abi1‐1 (abscisic acid),
Bikash Baral, Mikael Brosché
wiley   +1 more source

CD36 and Its Role in Obesity

Obesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
wiley   +1 more source

UCK2-dependent conversion of cytidine to CTP is required for CTP uptake by <i>Chlamydia trachomatis</i>. [PDF]

MicroPubl Biol
Blanchet L, Subtil A.
europepmc   +1 more source

Compartmentalized thymidine phosphorylation by mitochondrial nucleotide kinases TK2 and CMPK2. [PDF]

J Biol Chem
Ward AS, Kamath VG, Hsiung CH, Lizenby ZJ, Gillish AG, Kohtz DS, McKee EE.   +6 more
europepmc   +1 more source

Addition of hydroxyurea (hydroxycarbamide) enhances the efficacy of fludarabine/cytarabine-based salvage regimens against acute myeloid leukaemia. [PDF]

Br J Haematol
Lilienthal I, Tao S, Nilsson C, Leonard E, Zhang R, Sorteberg AL, Fredrikson L, Xagoraris I, Fard SS, Tsesmetzis N, Zachariadis V, Cai H, Sandhow L, Langebäck A, Bohlin A, Tamm KP, Bengtzén S, Schinazi RF, Lehmann S, Kim B, Rassidakis GZ, Qian H, Jädersten M, Herold N.   +23 more
europepmc   +1 more source

The NUDIX hydrolase NUDT5 regulates thiopurine metabolism and cytotoxicity. [PDF]

J Clin Invest
Maillard M, Nishii R, Vu HS, Bhattarai KR, Yang W, Li J, Hofmann U, Savic D, Bhatia S, Schwab M, Ni M, Yang JJ.   +11 more
europepmc   +1 more source

Enzyme cascades for nucleotide sugar regeneration in glycoconjugate synthesis. [PDF]

Appl Microbiol Biotechnol
Elling L.
europepmc   +1 more source

Increased nucleotide metabolism alleviates Alzheimer's disease pathology. [PDF]

Cell Death Dis
Yu Y, Miller MB, Huang AY, Tan BWZ, Celardo I, Leal NS, Loh SHY, Martins LM.   +7 more
europepmc   +1 more source