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The Role of Gene Duplication in the Evolution of Purine Nucleotide Salvage Pathways
Origins of life and evolution of the biosphere, 1998Purine nucleotides are formed de novo by a widespread biochemical route that may be of monophyletic origin, or are synthesized from preformed purine bases and nucleosides through different salvage pathways. Three monophyletic sets of purine salvage enzymes, each of which catalyzes mechanistically similar reactions, can be identified: (a) adenine ...
A, Becerra, A, Lazcano
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Interrelation between salvage of purine nucleotides and protein synthesis in rat heart cells
Archives of Biochemistry and Biophysics, 1985The effect of transition from a respiring to a respiration-inhibited state on the rate of protein synthesis was investigated in glycolyzing, cultured rat heart cells. The rate was found to be significantly lower after blocking respiration, and it was further decreased by L-lactate.
K, Ravid, P, Diamant, Y, Avi-Dor
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Plant Physiology and Biochemistry, 2008
Pyrimidine nucleotide metabolism was studied in tobacco callus cultured for 21days under shoot-forming (SF) and non-shoot-forming (NSF) conditions by following the metabolic fate of orotic acid, a precursor of the de novo pathway, and uridine and uracil, intermediates of the salvage and degradation pathways respectively. Nucleic acid synthesis was also
Natalia, Loukanina +4 more
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Pyrimidine nucleotide metabolism was studied in tobacco callus cultured for 21days under shoot-forming (SF) and non-shoot-forming (NSF) conditions by following the metabolic fate of orotic acid, a precursor of the de novo pathway, and uridine and uracil, intermediates of the salvage and degradation pathways respectively. Nucleic acid synthesis was also
Natalia, Loukanina +4 more
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Biochemical Pharmacology, 1982
The activity of uridine-cytidine kinase (Urd-Cyd kinase). a key enzyme in the salvage of pyrimidine nucleosides, averaged 0.86 +/- 0.16 (S.E.M.) nmole uridine phosphates . min-1 . (mg protein)-1 in fifty-three specimens of human colorectal adenocarcinomas.
N K, Ahmed, R C, Haggitt, A D, Welch
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The activity of uridine-cytidine kinase (Urd-Cyd kinase). a key enzyme in the salvage of pyrimidine nucleosides, averaged 0.86 +/- 0.16 (S.E.M.) nmole uridine phosphates . min-1 . (mg protein)-1 in fifty-three specimens of human colorectal adenocarcinomas.
N K, Ahmed, R C, Haggitt, A D, Welch
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Canadian Journal of Microbiology, 1989
The specific activity of adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) and adenosine phosphorylase (EC 2.4.2.-), two enzymes involved in the utilization of exogenous adenine, was measured in extracts of myxamoebae-swarm cells of Physarum flavicomum undergoing growth, microcyst formation (control), and during adenine inhibition of encystment ...
A, Cumaraswamy, H R, Henney
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The specific activity of adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) and adenosine phosphorylase (EC 2.4.2.-), two enzymes involved in the utilization of exogenous adenine, was measured in extracts of myxamoebae-swarm cells of Physarum flavicomum undergoing growth, microcyst formation (control), and during adenine inhibition of encystment ...
A, Cumaraswamy, H R, Henney
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Plant Science, 2005
Abstract To estimate the operation of the de novo and salvage pathways of pyridine nucleotide synthesis, [3H]quinolinic acid, an intermediate of the de novo synthesis, and [14C]nicotinamide and [14C]nicotinic acid, substrates of the salvage pathways, were administered to cultured white spruce (Picea glauca) and Madagascar periwinkle (Catharanthus ...
Hiroshi Ashihara +4 more
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Abstract To estimate the operation of the de novo and salvage pathways of pyridine nucleotide synthesis, [3H]quinolinic acid, an intermediate of the de novo synthesis, and [14C]nicotinamide and [14C]nicotinic acid, substrates of the salvage pathways, were administered to cultured white spruce (Picea glauca) and Madagascar periwinkle (Catharanthus ...
Hiroshi Ashihara +4 more
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1995
Erythrocytes from patients with uraemia invariably contain markedly increased ATP concentration1. Other effects of uraemia on erythrocyte metabolism are: elevation of GTP, ITP and 2.3-DPG concentration1–2, increased utilisation of glucose, higher lactate production or decreased Na/K dependent membrane ATP-ase activity3, 4.
M, Marlewski +6 more
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Erythrocytes from patients with uraemia invariably contain markedly increased ATP concentration1. Other effects of uraemia on erythrocyte metabolism are: elevation of GTP, ITP and 2.3-DPG concentration1–2, increased utilisation of glucose, higher lactate production or decreased Na/K dependent membrane ATP-ase activity3, 4.
M, Marlewski +6 more
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Molecular Characterization of RNA degradation and nucleotide salvage in the vacuole of Arabidopsis
The vacuole is a membrane-bound organelle that plays an essential role in the hydrolysis of biomolecules and nutrients remobilization through the action of various lytic enzymes including RNS2, a T2 RNase of Arabidopsis. By autophagy-related pathways and a SKI2-dependent direct uptake mechanism, RNA is delivered to vacuoles and degraded by RNS2 to ...openaire +2 more sources