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De novo and salvage biosynthetic pathways of pyridine nucleotides and nicotinic acid conjugates in cultured plant cells

Plant Science, 2005
Abstract To estimate the operation of the de novo and salvage pathways of pyridine nucleotide synthesis, [3H]quinolinic acid, an intermediate of the de novo synthesis, and [14C]nicotinamide and [14C]nicotinic acid, substrates of the salvage pathways, were administered to cultured white spruce (Picea glauca) and Madagascar periwinkle (Catharanthus ...
Yuling Yin   +4 more
openaire   +2 more sources

Accelerated Purine Base Salvage — A Possible Cause of Elevated Nucleotide Pool in the Erythrocytes of Patients with Uraemia

1995
Erythrocytes from patients with uraemia invariably contain markedly increased ATP concentration1. Other effects of uraemia on erythrocyte metabolism are: elevation of GTP, ITP and 2.3-DPG concentration1–2, increased utilisation of glucose, higher lactate production or decreased Na/K dependent membrane ATP-ase activity3, 4.
Julian Swierczynski   +6 more
openaire   +3 more sources

Genetical and biochemical evidence that a novel dinucleoside polyphosphate coordinates salvage and de novo nucleotide biosynthetic pathways in mammalian cells

Biochemical and Biophysical Research Communications, 1977
Abstract Studies with ‘wild type’ Chinese hamster ovary cells and mutant derivatives defective in purine salvage and de novo nucleotide biosynthesis pathways have brought to light the possibility that an unusual dinucleoside polyphosphate, HS-3 (see appendix) is a crucial regulator of these two pathways.
Herb B. LéJohn, Swee Han Goh
openaire   +3 more sources

Three Arabidopsis UMP kinases have different roles in pyrimidine nucleotide biosynthesis and (deoxy)CMP salvage

The Plant Cell
Abstract Pyrimidine nucleotide monophosphate biosynthesis ends in the cytosol with uridine monophosphate (UMP). UMP phosphorylation to uridine diphosphate (UDP) by UMP KINASEs (UMKs) is required for the generation of all pyrimidine (deoxy)nucleoside triphosphates as building blocks for nucleic acids and central metabolites like UDP ...
Jannis Rinne   +8 more
openaire   +3 more sources

Salvage Therapy for Multiple Myeloma with Lenalidomide-Based Regimens: Impact of Single Nucleotide Polymorphisms Related to miRNA Pathways

open access: closed, 2014
Carlos Fernández de Larrea   +9 more
openalex   +1 more source

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