Results 41 to 50 of about 30,194 (292)
Plant Physiology and Biochemistry, 2007 Pyrimidine nucleotide metabolism was studied in tobacco callus cultured for 21days under shoot-forming (SF) and non-shoot-forming (NSF) conditions by following the metabolic fate of orotic acid, a precursor of the de novo pathway, and uridine and uracil, intermediates of the salvage and degradation pathways respectively. Nucleic acid synthesis was also
Natalia Loukanina +4 more
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Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]
, 2014 BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Arozarena, Imanol +5 more
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Nucleobase and nucleoside transport and integration into plant metabolism
Frontiers in Plant Science, 2014 Nucleotide metabolism is an essential process in all living organisms. Besides newly synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides i.e.
Christopher eGirke +3 more
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Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes. [PDF]
, 2009 BackgroundA growing number of realistic in silico models of metabolic functions are being formulated and can serve as 'dry lab' platforms to prototype and simulate experiments before they are performed.
Jamshidi, Neema, Palsson, Bernhard O
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Molecules, 2021 Hydroxycamptothecin (SN38) is a natural plant extract isolated from Camptotheca acuminate. It has a broad spectrum of anticancer activity through inhibition of DNA topoisomerase I, which could affect DNA synthesis and lead to DNA damage. Thus, the action
Yan Li +6 more
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Cells, 2019 Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is a key enzyme in de novo nucleotide synthesis and nucleotide salvage synthesis pathways that are critical for purine and pyrimidine biosynthesis.
Jifu Li +3 more
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Toxoplasma gondii: Are Host Cell Adenosine Nucleotides a Direct Source for Purine Salvage?
Experimental Parasitology, 2000 Abstract Ngo, H. M., Ngo, E. O., Bzik, D. J., and Joiner, K. A. 2000. Toxoplasma gondii: Are host cell adenosine nucleotides a direct source for purine salvage? Experimental Parasitology95, 148–153.
Huân M. Ngô +3 more
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Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis [PDF]
, 2005 Protein structures from the causative agent of anthrax (Bacillus anthracis) are being determined as part of a structural genomics programme. Amongst initial candidates for crystallographic analysis are enzymes involved in nucleotide biosynthesis, since ...
Blagova, E V +6 more
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The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters [PDF]
, 2014 The human genome encodes 53 members of the solute carrier family 25 (SLC25), also called the mitochondrial carrier family, many of which have been shown to transport inorganic anions, amino acids, carboxylates, nucleotides, and coenzymes across the inner
Agrimi, G. +6 more
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Microbial Biotechnology, 2023 Human infections caused by Brucella (called brucellosis) are among the most common zoonoses worldwide with an estimated 500,000 cases each year. Since chronic Brucella infections are extremely difficult to treat, there is an urgent need for more ...
Jiuwang Yu +9 more
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