Results 241 to 250 of about 551,715 (314)

Varietal differences and process adaptability for precision processing of <i>Lentinula edodes</i>: a systematic evaluation based on volatile and non-volatile flavor compounds. [PDF]

Food Chem X
Zhang R, Zhao X, Bao R, Li C, Hu Q, Zhang Y, Ma G, Weng R.   +7 more
europepmc   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Metabolomic insights into formation and dynamic changes of taste in semi-dried Silver Carp (<i>Hypophthalmichthys molitrix</i>) throughout the drying process: key roles of metabolites derived from protein and nucleotide degradation. [PDF]

Food Chem X
Peng Y, Ouyang D, Tian M, Li Y, Li S, Wu J, Wang F, Liu Y, Li X.   +8 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

2'-hydroxyl modification improves enzymatic and thermal stability of mRNA. [PDF]

Mol Ther Nucleic Acids
Uchida S.
europepmc   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

Molecular Epidemiology of Enteric Viral Infections in Poultry Flocks in Southern Germany and the First Complete Genome Sequence of Avian <i>Sicinivirus</i>. [PDF]

Animals (Basel)
Moharam I, Brüggemann J, Schmitt F, Schade B, Böhm B, Kappe E, Emmrich F, Najar FZ, El-Mayet FS.   +8 more
europepmc   +1 more source

Assessment of miRNAs as transcriptional regulators in respiratory syncytial virus infection through computational analysis and molecular docking studies. [PDF]

PLoS One
Hassan M, Iqbal MS, Yasir M, Chun W, Yaseen Z, Shahzadi S, Peeples ME, Kloczkowski A.   +7 more
europepmc   +1 more source

Integrating Molecular Biology and Cryptography: A DNA and RNA-Based Framework for Secure Data Encryption. [PDF]

Int J Mol Sci
Akhtar MN, Awan JH, Asad AMS, Kim MY.
europepmc   +1 more source

Selective electrochemical discrimination of 3' isomiRs differing by two nucleotides.

Analyst
Ojeda J, Bruno N, Cover K, Zhang WC, Chumbimuni-Torres K.   +4 more
europepmc   +1 more source