Results 161 to 170 of about 2,194,144 (349)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Glutamate delta-1 receptors regulate a tonic excitatory conductance in the mouse bed nucleus of the stria terminalis and influence neuronal function [PDF]

Sara Y. Conley, Sarah E. Sizer, Madigan L. Bedard, Sara Faccidomo, Clyde W. Hodge, Zoé A. McElligott   +5 more
openalex   +1 more source

Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz‐F1 disrupted mice [PDF]

, 1995
Koh Shinoda, Hong Lei, Hironori Yoshii, Masatoshi Nomura, Mamoru Nagano, Hiroharu Shiba, Hiroshi Sasaki, Yoshio Osawa, Yasuharu Ninomiya, Ohtsura Niwa, Ken-ichirou Morohashi, En Li   +11 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.

, 1988
Tien‐Hsien Chang, Megan Clark, Arthur J. Lustig, Michael E. Cusick, John Abelson   +4 more
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

SOME PROPERTIES OF INTRINSIC NEURONS OF THE DORSAL LATERAL GENICULATE NUCLEUS OF THE RAT

, 1977
Ichiji Sumitomo, Kitsuya Iwama
openalex   +2 more sources

The Collectivity of Heavy Mesons in Proton-Nucleus Collisions

, 2020
Zhang, Cheng, Cyrille Marquet, Guang-You Qin, Shi, Yu, Wang, Lei, Shuyi Wei, Bo-Wen Xiao   +6 more
openalex   +1 more source

Manic episode with psychotic symptoms induced by subthalamic nucleus stimulation in a patient with Parkinson's disease [PDF]

, 2003
Jan Herzog, Julia Reiff, Paul Krack, Karsten Witt, Bettina Schrader, Dieter Müller, Günther Deuschl   +6 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source