Results 71 to 80 of about 1,379,939 (300)
Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to Cardiomyopathies
Frontiers in Physiology, 2018 Nuclear lamin A/C are crucial components of the intricate protein mesh that underlies the inner nuclear membrane and confers mainly nuclear and cytosolic rigidity.
Andrea Gerbino +3 more
doaj +1 more source
HIV-1 Gag Forms Ribonucleoprotein Complexes with Unspliced Viral RNA at Transcription Sites
Viruses, 2020 The ability of the retroviral Gag protein of Rous sarcoma virus (RSV) to transiently traffic through the nucleus is well-established and has been implicated in genomic RNA (gRNA) packaging Although other retroviral Gag proteins (human immunodeficiency ...
Kevin M. Tuffy +5 more
doaj +1 more source
Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]
, 2012 Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Herczeg, László +11 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cell Reports, 2017 Small heat shock proteins (HSPBs) contain intrinsically disordered regions (IDRs), but the functions of these IDRs are still unknown. Here, we report that, in mammalian cells, HSPB2 phase separates to form nuclear compartments with liquid-like properties.
Federica F. Morelli +15 more
doaj +1 more source
The intermediolateral nucleus: an ‘open’ or ‘closed’ nucleus?
Brain Research, 1986 The sympathetic preganglionic neurons located in the intermediolateral nucleus (IML) that project to the superior cervical ganglion of the rabbit were observed to have two major dendritic orientations after retrograde labeling with horseradish peroxidase. One projection extends longitudinally within IML.
P L, Vera +4 more
openaire +2 more sources
BFKL Pomeron calculus: Nucleus–nucleus scattering [PDF]
Nuclear Physics A, 2012 22pp.
Contreras, Carlos +2 more
openaire +6 more sources
Neuregulins in the nucleus [PDF]
, 2009 The neuregulins are a subset of the ligands for the epidermal growth factor receptor family of receptors. They can bind to these receptors and evoke a range of cellular responses.
Carol M. McClell +5 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Journal of Lipid Research, 2019 Phosphoinositide-specific phospholipases C (PI-PLCs) are involved in signaling pathways related to critical cellular functions, such as cell cycle regulation, cell differentiation, and gene expression.
Stefano Ratti +8 more
doaj +1 more source