Results 71 to 80 of about 1,356,858 (249)

Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease [PDF]

, 2001
The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson's disease. The question is an important one because synchronization will increase postsynaptic efficacy at subsequent projection targets.
Peter Brown, Vincenzo Di Lazzaro, Oliviero, A, Insola, A, Brown, Peter, Antonio Oliviero, Di Lazzaro, V, Mazzone, P, Brown, P, Pietro Tonali, Tonali, P, Paolo Mazzone, Angelo Insola   +12 more
core   +1 more source

Modelling the effects of deep brain stimulation in the pedunculopontine tegmental nucleus in Parkinson’s disease [PDF]

, 2014
Based on the belief that it is a locomotor control structure, the pedunculopontine tegmental nucleus (PPTg) has been considered a potential target for deep brain stimulation (DBS) for Parkinson’s disease (PD) patients with symptoms refractory to ...
Gut, Nadine Katrin
core   +2 more sources

Genetic control of isozymes in the primary gene pool Phaseolus lunatus L. [PDF]

Biotechnologie, Agronomie, Société et Environnement, 1999
Suitable electrophoretic separation methods of 34 isozymes from 17 enzyme systems resolved in Phaseolus lunatus L. (Lima bean) were developed. Data from the migration of the staining zones indicated that three loci control EST, GPI, IDH and MDH ...
Maquet A., Zoro-Bi I., Wathelet B., Baudoin J.P.   +3 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Beta-decay and structure of odd nuclei, suppression of weak forces in nuclei

Ядерна фізика та енергетика, 2019
Results of calculations in the framework of the dynamic collective model of probabilities of beta-transitions for more than 20 nuclei with mass numbers from А = 31 to А = 231 with one universal renormalization of weak interaction constants are presented.
A. A. Kurteva, V. E. Mitroshin
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]

, 2012
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Herczeg, László, Sipos, Máté T., Molnár, Csilla S., Vida, Barbara, Borsay, Beáta Á., Dhillo, Waljit S., Liposits, Zsolt, Hrabovszky, Erik, Rácz, Kálmán, Bloom, Stephen R., Ghatei, Mohammad A., Ciofi, Philippe   +11 more
core   +1 more source

Linking actions to outcomes : the role of the posterior pedunculopontine tegmental nucleus in instrumental learning [PDF]

, 2012
Located in the mesopontine tegmentum, the pedunculopontine tegmental nucleus (PPTg) is comprised principally of glutamatergic, cholinergic and GABAergic neurons.
MacLaren, Duncan A. A.
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav, Eckhard Wolf, Oliver Eickelberg, Fuchs Helmut, Alexander Bohla, Schmidt, Volker, Rülicke, T., Hrabě de Angelis, M., Rohožková, Jana, Alžběta Kalendová, Martin Hrabě de Angelis, Schmidt Volker, Dzijak, R., Kalendová, Alžběta, Rathkolb, Birgit, Hozák, Pavel, Dzijak Rastislav, Hans, Wolfgang, Ali Önder Yildirim, Rathkolb, B., Venit, Tomáš, Wolf Eckhard, Hans Wolfgang, Yildirim Ali Önder, Fuchs, H., Hozák Pavel, Bohla Alexander, Stoeger Tobias, Gailus-Durner, Valérie, Jana Rohožková, Hrabé de Angelis, Martin, Kahle-Stephan, M., Valérie Gailus-Durner, Wolf, E., Stoeger, Tobias, Thomas Rülicke, Gailus-Durner, V., Volker Schmidt, Kahle Michal, Helmut Fuchs, Kahle, Michal, Eickelberg, O., Kalendova, A., Venit Tomáš, Eickelberg Oliver, Bohla, A., Rastislav Dzijak, Michal Kahle, Rohožková Jana, Yildirim, A.Ö., Venit, T., Eickelberg, Oliver, Stöger, T., Wolfgang Hans, Rülicke Thomas, Hans, W., Rohozkova, J., Rathkolb Birgit, Bohla, Alexander, Birgit Rathkolb, Rülicke, Thomas, Tobias Stoeger, Tomáš Venit, Fuchs, Helmut, de Angelis Martin Hrabě, Schmidt, V., Yildirim, Ali Önder, Gailus-Durner Valérie, Wolf, Eckhard, Hozak, P., Kalendová Alžběta, Pavel Hozák, Venit, T. ; Dzijak, R. ; Kalendova, A. ; Kahle, M. ; Rohozkova, J. ; Schmidt, V. ; Rülicke, T. ; Rathkolb, B. ; Hans, W. ; Bohla, A. ; Eickelberg, O. ; Stöger, T. ; Wolf, E. ; Yildirim, A.Ö. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabé de Angelis, M. ; Hozak, P.   +72 more
core   +2 more sources