Time‐Restricted Feeding Alters Behavior in a Sex‐Specific Manner in Mice With Neuropathic Pain
Time‐restricted feeding (TRF) alleviates anxiety‐like behavior in male mice with neuropathic pain (NP), but not in females. Upon nerve injury, TRF altered the diurnal expression of transcripts in the hypothalamus. These findings suggest that TRF should be explored as a new therapeutic approach to alleviate the comorbid anxiety in NP.
Manqing Wen +3 more
wiley +1 more source
The nucleus accumbens to ventral pallidum pathway regulates social play behavior via sex-specific mechanisms in juvenile rats. [PDF]
Lee JDA +4 more
europepmc +1 more source
Targeting Multiple Gut‐Brain Pathways in Obesity: Rationale for Combination Pharmacotherapy
ABSTRACT Background As a disease of energy dysregulation, obesity involves metabolic, hormonal, and neural factors, the interconnection of which is referred to as the “gut‐brain axis.” Objective This review aimed to provide an overview of the clinical evidence of physiological and objective or subjective changes in eating behavior with gut hormone ...
Alexander D. Miras, Muzamil Hussain
wiley +1 more source
Gestational stress disrupts the neuroimmune environment in the nucleus accumbens of maternal rats. [PDF]
Dye CN +7 more
europepmc +1 more source
Abstract INTRODUCTION Physical activity is a promising non‐pharmacological approach to support brain health. Although prior studies suggest cognitive benefits, it remains unclear how exercise alters brain structure and connectivity on the Alzheimer's disease (AD) continuum and whether such neural changes translate to functional improvements. This study
Ravi Dadsena +6 more
wiley +1 more source
Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity. [PDF]
Yaakub SN +10 more
europepmc +1 more source
Ethanol Alters the Neurexin Landscape in Human Neuroblastoma Cells
It is currently unknown how ethanol exposure alters the landscape of the synaptic hubs, neurexins. Using IMR32 cells differentiated toward parvalbumin‐like neurons, we demonstrated an ethanol dose‐dependent, transcript and isoform‐specific loss of neurexins.
Clara C. Lowe +2 more
wiley +1 more source
Sex and Stress Govern the Function and Innervation of a Basolateral Amygdala to Nucleus Accumbens Corticotropin-Releasing Hormone/GABA-Expressing Projection. [PDF]
Taniguchi L +9 more
europepmc +1 more source
Orexin signalling in the nucleus accumbens promotes arousal from isoflurane anaesthesia and restores communication between the nucleus accumbens and frontal cortex. [PDF]
Huo J +6 more
europepmc +1 more source
Sex Difference in Brain Responses During Short Abstinence in People With Internet Gaming Disorder
Short‐term abstinence in internet gaming disorder (IGD) reveals altered functional connectivity in executive control and reward brain regions compared to recreational users. Males with IGD show stronger functional connectivity between frontal and insular regions than females, indicating greater disruption in cognitive control.
Shaoyu Cui, Xuefeng Xu, Guangheng Dong
wiley +1 more source

