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5-HT<sub>2C</sub> receptors in the nucleus accumbens constrain the rewarding effects of MDMA. [PDF]
Pomrenze MB +14 more
europepmc +1 more source
Distribution of Serotonergic Transporter Innervation in the Nucleus Accumbens and Ventral Pallidum Is Highly Conserved Among Primates. [PDF]
Smith HN +5 more
europepmc +1 more source
Cocaine-induced gene regulation in D1 and D2 neuronal ensembles of the nucleus accumbens. [PDF]
Mews P +4 more
europepmc +1 more source
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Nucleus accumbens and impulsivity
Progress in Neurobiology, 2010The multifaceted concept of impulsivity implies that different impulsivity aspects, mediated by different neural processes, influence behavior at different levels. The nucleus accumbens (NAc) is a key component of the neural processes regulating impulsivity.
Basar, K. +5 more
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Nucleus Accumbens Surgery for Addiction
World Neurosurgery, 2013Opiate addiction remains intractable in a large percentage of patients, and relapse is the biggest hurdle to recovery because of psychological dependence. Multiple studies identify a central role of the nucleus accumbens (NAc) in addiction; several studies note decreased addictive behavior after interventions in this area.Based on animal experiments ...
Nan, Li +9 more
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Appetitive Mapping of the Human Nucleus Accumbens
Biological Psychiatry, 2022ABSTRACTThere is strong evidence for the putative role of the nucleus accumbens (NAc) in appetitive motivation. A first-in-human feasibility trial of responsive deep brain stimulation (rDBS) for loss of control eating provided a rare opportunity to examine the physiologic and structural underpinnings of NAc function in a human participant with ...
Jonathon J. Parker +10 more
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Connections of the nucleus accumbens
Brain Research, 1976Reports from previous works has given different classifications for the nucleus accumbens. There also appears to be a general lack of information regarding the fiber connections of the nucleus. The present investigation was undertaken to clarify the connections of this structure.
E W, Powell, R B, Leman
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Differential Modulation of Nucleus Accumbens Synapses
Journal of Neurophysiology, 2002The nucleus accumbens (NAcc) is a brain region involved in functions ranging from motivation and reward to feeding and drug addiction. The NAcc is typically divided into two major subdivisions, the shell and the core. The primary output neurons of both of these areas are medium spiny neurons (MSNs), which are quiescent at rest and depend on the ...
James M, Brundege, John T, Williams
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