Results 241 to 250 of about 473,018 (289)

Thermosensitive injectable decellularized nucleus pulposus hydrogel as an ideal biomaterial for nucleus pulposus regeneration

Journal of Biomaterials Applications, 2020
Extracellular matrix loss is one of the early manifestations of intervertebral disc degeneration. Stem cell-based tissue engineering creates an appropriate microenvironment for long term cell survival, promising for NP regeneration. We created a decellularized nucleus pulposus hydrogel (DNPH) from fresh bovine nucleus pulposus.
Lei Yu, Zi-Jie Sun, Quan-Chang Tan, Shuang Wang, Wei-Heng Wang, Xiang-Qun Yang, Xiao-Jian Ye   +6 more
openaire   +3 more sources

lncRNA HOTAIR upregulates autophagy to promote apoptosis and senescence of nucleus pulposus cells

Journal of Cellular Physiology, 2020
Intervertebral disc degeneration (IDD) is a complex and chronic disease that involves disc cell senescence, death, and extracellular matrix (ECM) degradation.
Shengfeng Zhan, Kun Wang, Q. Xiang, Yu Song, Shuai Li, Hang Liang, Rongjin Luo, B. Wang, Zhiwei Liao, Yukun Zhang, Cao Yang   +10 more
semanticscholar   +1 more source

Inflammatogenic Properties of Nucleus Pulposus

Spine, 1995
The inflammatogenic properties of nucleus pulposus were assessed in two experimental models previously used for screening of inflammatogenic properties of other substances. This study was performed to assess the inflammatogenic properties of nucleus pulposus in models previously screened for other substances.Previous experimental studies, as well as ...
Strömberg J, Ulf Nannmark, Björn Rydevik, Kjell Olmarker, Jesper Blomquist, Peter Thomsen   +5 more
openaire   +3 more sources

Apoptosis in the Sequestrated Nucleus Pulposus Compared to the Remaining Nucleus Pulposus in the Same Patient

Spine, 2011
Both sequestrated nucleus pulposus (SNP) and the remaining nucleus pulposus (RNP) were studied from the discs of the same patient to evaluate apoptosis using immunohistochemical staining.To compare apoptosis of the SNP and the RNP in the disc of the same patient.Many studies have been conducted on the natural history and apoptosis of the herniated ...
Bae-Gyun Kim, Kee-Yong Ha, In-Soo Oh, Jun-Yeong Seo, Ki-Won Kim   +4 more
openaire   +3 more sources

Hernia of the Nucleus Pulposus

The British Journal of Radiology, 1934
In the radiological examination of the spine one frequently sees in association with kyphoses very varied contours of the upper and lower vertebral margins. They may appear wavy or show irregular sclerotic patches or even appear notched. These irregularities are apt to be dismissed, the mild ones as variations of the normal and the more gross ones ...
openaire   +2 more sources

Is the Nucleus Pulposus a Solid or a Fluid? Mechanical Behaviors of the Nucleus Pulposus of the Human Intervertebral Disc

Spine, 1996
A new technique to measure the viscoelastic behavior of the nucleus pulposus in shear was used to assess its solid and fluid characteristics.To review existing knowledge on mechanical behaviors of the nucleus pulposus, and to develop a new technique to study the viscoelastic behaviors of isolated nucleus pulposus samples in torsional (pure) shear under
Van C. Mow, Lori A. Setton, James C. Iatridis, Mark Weidenbaum   +3 more
openaire   +2 more sources

The Origin of Chondrocytes in the Nucleus Pulposus and Histologic Findings Associated With the Transition of a Notochordal Nucleus Pulposus to a Fibrocartilaginous Nucleus Pulposus in Intact Rabbit Intervertebral Discs

Spine, 2003
Intact rabbit lumbar intervertebral discs were examined histologically.To demonstrate the origin of chondrocytes in the nucleus pulposus, and to document histologic findings associated with the transition of a notochordal to a fibrocartilaginous nucleus pulposus.A human nucleus pulposus undergoes a chronological transition from a notochordal to a ...
Tae-Hong Lim, Koichi Masuda, Ki-Won Kim, Howard S. An, Jesse G. Kim, Soon-Taek Jeong   +5 more
openaire   +3 more sources

Spontaneous regression of herniated nucleus pulposus

American Journal of Roentgenology, 1985
Spontaneous regression of herniated nucleus pulposus has not been previously documented. Reported here are 11 patients in whom there was unequivocal regression or disappearance of a herniated lumbar disk on follow-up CT study. Two patients with herniated disks were without symptoms.
M E Haskin, J G Teplick
openaire   +3 more sources

Antibiotic Penetration into Rabbit Nucleus Pulposus

Spine, 1987
A rabbit model was used to determine the penetration of four commonly used antibiotics (clindamycin, tobramycin, cephalothin, and oxacillin) into the nucleus pulposus after receiving an 8-hour course of intramuscular antibiotic injections. Clindamycin and tobramycin achieved therapeutic levels in the nucleus pulposus and both were present in greater ...
Richard H. Rothman, Frank J. Eismont, Carl T. Brighton, Sam W. Wiesel   +3 more
openaire   +3 more sources

Mucopolysaccharides from Cartilage and Nucleus Pulposus

Nature, 1957
Meyer and Rapport1 described the isolation from hyaline cartilage of two chondroitin sulphates, A and C. The only differences so far reported2 between these are in the specific optical rotation and alcohol solubility of their calcium, salts. Orr3 found that chondroitin sulphate from cartilage gives an infra-red spectrum which suggests that the product ...
F Happey, A Naylor, G Bernardi
openaire   +3 more sources