Results 41 to 50 of about 18,006 (243)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Null controllability of degenerate parabolic cascade systems

open access: yesPortugaliae Mathematica, 2011
In this paper, we study the null controllability of degenerate semilinear cascade parabolic systems with one control force. The key tool is the Carleman estimates developed recently for degenerate one dimension parabolic equations. We develop a Carleman estimate for these systems and then an observability inequality for the linear adjoint system.
Ait Ben Hassi, El Mustapha   +3 more
openaire   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Controllability results for some nonlinear coupled parabolic systems by one control force [PDF]

open access: yes, 2006
In this paper, we present new controllability results for some nonlinear coupled parabolic systems considered in a bounded domain Ω of IRN (with N ≥ 1 being arbitrary) when the control force acts on a unique equation of the system through an ...
González Burgos, Manuel   +1 more
core  

Observability Inequality of Backward Stochastic Heat Equations for Measurable Sets and Its Applications

open access: yes, 2016
This paper aims to provide directly the observability inequality of backward stochastic heat equations for measurable sets. As an immediate application, the null controllability of the forward heat equations is obtained.
Yang, Donghui, Zhong, Jie
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Null controllability of viscous Hamilton–Jacobi equations

open access: yesAnnales de l'Institut Henri Poincaré C, Analyse non linéaire, 2012
We study the problem of null controllability for viscous Hamilton–Jacobi equations in bounded domains of the Euclidean space in any space dimension and with controls localized in an arbitrary open nonempty subset of the domain where the equation holds.
PORRETTA, ALESSIO, Zuazua, E.
openaire   +4 more sources

Null controllability of Grushin-type operators in dimension two

open access: yes, 2013
International audienceWe study the null controllability of the parabolic equation associated with the Grushin-type operator in the rectangle, under an additive control supported in an open subset of the rectangle.
Beauchard, Karine   +2 more
core   +4 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

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