Results 51 to 60 of about 583,857 (303)

On the Importance of Modeling the Invisible World of Underlying Effect Sizes

open access: yesSocial Psychological Bulletin, 2023
The headline findings from the Open Science Collaboration (2015)―namely, that 36% of original experiments replicated at p < .05, with the overall replication effect sizes being half as large as the original effects―cannot be meaningfully interpreted ...
Brent M. Wilson, John T. Wixted
doaj   +1 more source

Is There a Free Lunch in Inference? [PDF]

open access: yes, 2016
The field of psychology, including cognitive science, is vexed by a crisis of confidence. Although the causes and solutions are varied, we focus here on a common logical problem in inference.
Morey, Richard D.   +4 more
core   +1 more source

Reducing our dependence on null hypothesis testing: A key to enhance the reproducibility and credibility of our science

open access: yesSA Journal of Industrial Psychology, 2019
Problemification: Over-reliance on null hypothesis significance testing (NHST) is one of the most important causes of the emerging crisis over the credibility and reproducibility of our science.
Kevin R. Murphy
doaj   +1 more source

Danger: High Power! – Exploring the Statistical Properties of a Test for Random Forest Variable Importance [PDF]

open access: yes, 2008
Random forests have become a widely-used predictive model in many scientific disciplines within the past few years. Additionally, they are increasingly popular for assessing variable importance, e.g., in genetics and bioinformatics.
Strobl, Carolin, Zeileis, Achim
core   +2 more sources

Null Hypothesis Significance Testing: A Brief Review

open access: yes, 2021
Null hypothesis significance testing (NHST) dominates the interpretation of quantitative data analysis in education, psychology, and other social science fields (Shaver, 1993). Meanwhile, the use of NHST has been under enduring and intense criticisms (Carver, 1978; Cohen, 1997; Cumming, 2013; Thompson, 1993, 1996, 1999). In 2015, the journal, Basic and
openaire   +2 more sources

A method for parameter hypothesis testing in nonparametric regression with Fourier series approach

open access: yesMethodsX, 2023
Nonparametric regression model with the Fourier series approach was first introduced by Bilodeau in 1994. In the later years, several researchers developed a nonparametric regression model with the Fourier series approach.
Mustain Ramli   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Philosophical Preconditions Guide Null Hypothesis Significance Testing in Empirical Psychology

open access: yesNordicum-Mediterraneum
To mathematize is closely related to the ideal of scientific objectivity, claiming bias-free results. In this respect, mathematization may substantiate the belief that significance testing could prove or disprove a hypothesis, since it is considered bias-
Fredrik Dreyer Moe
doaj   +1 more source

Unsupervised empirical Bayesian multiple testing with external covariates

open access: yes, 2008
In an empirical Bayesian setting, we provide a new multiple testing method, useful when an additional covariate is available, that influences the probability of each null hypothesis being true.
Ferkingstad, Egil   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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