Results 91 to 100 of about 566,246 (303)

NULL ENERGY CONDITION AND DARK ENERGY MODELS [PDF]

open access: yesModern Physics Letters A, 2008
Null Energy Condition (NEC) requires the equation of state (EoS) of the universe wu satisfy wu ≥ -1, which implies, for instance in a universe with matter and dark energy dominating wu = w m Ω m + w de Ω de = w de Ω de ≥ -1. In this paper we study constraints on the dark energy models from the requirement of the NEC.
Qiu, Taotao, Cai, Yi-Fu, Zhang, Xin-Min
openaire   +2 more sources

Null-sampling for interpretable and fair representations

open access: yes, 2020
We propose to learn invariant representations, in the data domain, to achieve interpretability in algorithmic fairness. Invariance implies a selectivity for high level, relevant correlations w.r.t.
Novi Quadrianto (4465081)   +3 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Mechanisms of bacterial and fungal community assembly in leaf miners during transition from natural to laboratory environments

open access: yesFrontiers in Microbiology
Environmental heterogeneity partly drives microbial succession in arthropods, while the microbial assembly mechanisms during environmental changes remain largely unknown.
Yu-Xi Zhu   +5 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Size distortions of tests of the null hypothesis of stationarity: Evidence and implications for applied work [PDF]

open access: yes
It is common in applied econometrics to test the null hypothesis of a level-stationary process against the alternative of a unit root process. We show that the use of conventional asymptotic critical values for the stationarity tests of Kwiatkowski et al.
Kilian, Lutz, Caner, Mehmet
core  

Statistical challenges in null model analysis

open access: yes, 2011
Th is review identifi es several important challenges in null model testing in ecology: 1) developing randomization algorithms that generate appropriate patterns for a specifi ed null hypothesis; these randomization algorithms stake out a middle ground ...
Ulrich, Werner   +3 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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